Product Information
APTENSIO XR 50 MG CAPSULE is a brand product labeled by Rhodes Pharmaceuticals L.P., priced at $7.9978 per EA under NDC 42858040645. Its NADAC has been published 288 times since Apr 18, 2018.
FDA first approved this application on Apr 17, 2015. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Rhodes Pharmaceuticals L.P.NDC
42858040645
Classification
Brand
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
7/23/2025
Active Ingredients
METHYLPHENIDATE HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA205831FDA Approved
4/17/2015
TE Code
AB3
On Market Since
4/17/2015
Pharmacological Classes
Price Statistics
The NADAC for APTENSIO XR 50 MG CAPSULE has been published 288 times since Apr 18, 2018, and over the history we have for it it has risen 16.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.9978 per EA |
|---|---|
| All-time high | $8.0468 (Aug 11, 2021) |
| All-time low | $6.8627 (Apr 18, 2018) |
| 52-week high | $7.9978 |
| 52-week low | $7.9978 |
| Median price | $7.9978 |
| Average price | $7.8874 |
| Largest weekly change | +10.0% (Jun 6, 2018) |
| Weeks tracked | 288 |
| Tracking since | Apr 18, 2018 |
1W
N/A
1M
N/A
3M
0.0%
6M
0.0%
1Y
0.0%
3Y
-0.6%
5Y
-0.6%
All
+16.5%
Last surveyed Jul 15, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 82% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of APTENSIO XR 50 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for APTENSIO XR 50 MG CAPSULE, manufactured by Rhodes Pharmaceuticals L.P., is $7.9978 per EA (NDC 42858040645), effective Jul 15, 2026.
How has the price of APTENSIO XR 50 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for APTENSIO XR 50 MG CAPSULE has risen 16.5%. It has been tracked across 288 weekly CMS publications since Apr 18, 2018.
What are the highest and lowest recorded NADAC prices for APTENSIO XR 50 MG CAPSULE?
Since Apr 18, 2018, the NADAC for APTENSIO XR 50 MG CAPSULE has ranged from a low of $6.8627 (Apr 18, 2018) to a high of $8.0468 (Aug 11, 2021), with a median of $7.9978 per EA.
Are there cheaper alternatives to APTENSIO XR 50 MG CAPSULE?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METHYLPHENIDATE CD 50 MG CAP, is $1.4616 per EA — about 82% below APTENSIO XR 50 MG CAPSULE.
Who manufactures APTENSIO XR 50 MG CAPSULE?
APTENSIO XR 50 MG CAPSULE (NDC 42858040645) is labeled by Rhodes Pharmaceuticals L.P., and CMS classifies it as a brand product.