Drug Markets/Methylphenidate Hydrochloride

Methylphenidate Hydrochloride

Brand names: Ritalin, Concerta

187 NDCs across 32 manufacturers|145 Generic,42 Brand

Methylphenidate is a central nervous system stimulant for ADHD and narcolepsy, sold as Ritalin (immediate-release) and Concerta (osmotic extended-release) among others. It is a Schedule II controlled substance with DEA production quotas, and the market has seen recurring shortages since 2022. Because the extended-release products use several distinct, non-interchangeable release mechanisms, per-unit prices vary enormously between generic IR tablets and branded long-acting forms.

▸ More about this market

Methylphenidate Hydrochloride is used to treat attention deficit disorder with hyperactivity, depressive disorder and narcolepsy, per the National Library of Medicine's MED-RT classification. The brand product was first FDA-approved before 1982, and the first generic was approved Jan 1, 1982. FDA's Orange Book lists 135 AB-rated (therapeutically equivalent) products for this ingredient.

Methylphenidate Hydrochloride is available as 187 NDCs from 32 manufacturers (145 generic, 42 brand), with NADAC prices from $0.09 to $21.35 per EA — the most expensive product costs about 249× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Active FDA drug shortage

34 Methylphenidate Hydrochloride presentations are currently listed in FDA's drug shortage database (first posted Jul 26, 2023). Shortages can move NADAC prices in the following weeks.

Total NDCs

187

145G / 42B

Manufacturers

32

competing in market

Price Spread

$0.09 – $21.35

per EA, 171 of 187 NDCs

7d Activity

50↑78↓56 flat

avg -0.8% WoW · of 187 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Explore this market from other angles

Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.

Top supplier

SpecGx LLC manufacturer profile

Open the supplier page for the manufacturer with the strongest footprint in this market.

Lead class

Central Nervous System Stimulant class view

See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.

Trend hub

Latest market trends

Move from this single molecule into the current cross-market mover and volatility view.

Guide

How to interpret NADAC

Review the benchmark methodology behind the prices and spreads shown on this market page.

Manufacturer Breakdown

32 manufacturers producing METHYLPHENIDATE HYDROCHLORIDE(2 pricing outliers)

SpecGx LLC
17 NDCs
$0.8791
avg/unit
Rhodes Pharmaceuticals L.P.
14 NDCs
$6.1022
avg/unit
Actavis Pharma, Inc.
11 NDCs
$2.9255
avg/unit
Camber Pharmaceuticals Inc.
10 NDCs
$0.9478
avg/unit
Lannett Company Inc.
10 NDCs
$1.2128
avg/unit
Amneal Pharmaceuticals of New York LLC
9 NDCs
$1.0983
avg/unit
Trigen Laboratories, LLC
8 NDCs
$9.0146
avg/unit
Sun Pharmaceutical Industries Inc.
8 NDCs
$2.5101
avg/unit
Lupin Pharmaceuticals Inc.
8 NDCs
$0.9306
avg/unit
Vertical Pharmaceuticals, LLC
7 NDCs
$13.2919
avg/unit
Novartis Pharmaceuticals Corporation
7 NDCs
$7.5496
avg/unit
NextWave Pharmaceuticals, Inc
7 NDCs
$6.8165
avg/unit
Granules Pharmaceuticals Inc.
7 NDCs
$2.7628
avg/unit
Dr. Reddy's Laboratories Inc.
6 NDCs
$3.1732
avg/unit
AvPAK
6 NDCs
$0.5107
avg/unit
American Health Packaging
6 NDCs
$0.5023
avg/unit
Ironshore Pharmaceuticals Inc.
High Outlier
5 NDCs
$15.3995
avg/unit
KVK-Tech Inc.
5 NDCs
$0.1445
avg/unit
Janssen Pharmaceuticals Inc.
4 NDCs
$13.0505
avg/unit
Rising Pharma Holdings Inc.
3 NDCs
$2.0874
avg/unit
Teva Pharmaceuticals USA Inc.
3 NDCs
$1.8176
avg/unit
Sandoz Inc.
3 NDCs
$1.1871
avg/unit
Ascend Laboratories, LLC
3 NDCs
$0.1621
avg/unit
Nivagen Pharmaceuticals Inc.
3 NDCs
$0.1621
avg/unit
Accord Healthcare Inc.
3 NDCs
$0.1621
avg/unit
Solco Healthcare US LLC
3 NDCs
$0.1621
avg/unit
Mayne Pharma
2 NDCs
$2.0525
avg/unit
SHIONOGI INC.
2 NDCs
$0.1962
avg/unit
Eywa Pharma Inc
2 NDCs
$0.0990
avg/unit
Quagen Pharmaceuticals LLC
2 NDCs
$0.0990
avg/unit
Cranbury Pharmaceuticals, LLC
2 NDCs
$0.0990
avg/unit
NorthStar Rx LLC
High Outlier
1 NDC
$16.5088
avg/unit

Drug Portfolio

187 NDCs total, 187 shown

Drug ↕Price 7d Change ↕
RELEXXII ER 63 MG TABLET
$21.3526
per EA
-0.08%
METHYLPHENIDATE ER 63 MG TAB
$18.8744
per EA
+0.37%
METHYLPHENIDATE ER 45 MG TAB
$17.5060
per EA
-1.48%
METHYLPHENIDATE ER 72 MG TAB
$16.5088
per EA
-1.36%
METHYLPHENIDATE ER 72 MG TAB
$16.5088
per EA
-1.36%
METHYLPHENIDATE ER 72 MG TAB
$16.5088
per EA
-1.36%
METHYLPHENIDATE ER 72 MG TAB
$16.4981
per EA
—
JORNAY PM 40 MG CAPSULE
$15.4051
per EA
-0.02%
JORNAY PM 60 MG CAPSULE
$15.4019
per EA
-0.02%
JORNAY PM 80 MG CAPSULE
$15.4015
per EA
0.00%
JORNAY PM 100 MG CAPSULE
$15.3960
per EA
+0.02%
JORNAY PM 20 MG CAPSULE
$15.3930
per EA
-0.02%
CONCERTA ER 54 MG TABLET
$14.1797
per EA
-0.02%
CONCERTA ER 36 MG TABLET
$13.0427
per EA
-0.02%
RELEXXII ER 54 MG TABLET
$12.7779
per EA
—
RELEXXII ER 54 MG TABLET
$12.7779
per EA
—
RITALIN LA 40 MG CAPSULE
$12.7255
per EA
—
CONCERTA ER 27 MG TABLET
$12.6543
per EA
+0.01%
RITALIN LA 30 MG CAPSULE
$12.3878
per EA
—
CONCERTA ER 18 MG TABLET
$12.3253
per EA
-0.03%
RITALIN LA 20 MG CAPSULE
$12.1023
per EA
—
RITALIN LA 10 MG CAPSULE
$12.0700
per EA
—
QUILLICHEW ER 20 MG CHEW TAB
$11.9002
per EA
-0.06%
QUILLICHEW ER 30 MG CHEW TAB
$11.8844
per EA
-0.03%
QUILLICHEW ER 40 MG CHEW TAB
$11.8720
per EA
-0.05%
RELEXXII ER 36 MG TABLET
$11.7428
per EA
-1.00%
RELEXXII ER 36 MG TABLET
$11.7428
per EA
-1.00%
RELEXXII ER 27 MG TABLET
$11.3247
per EA
-1.33%
RELEXXII ER 27 MG TABLET
$11.3247
per EA
-1.33%
METHYLPHENIDATE ER(LA) 60 MG CP
$10.5151
per EA
-2.27%
METHYLPHENIDATE ER(LA) 60 MG CP
$10.5151
per EA
-2.27%
APTENSIO XR 60 MG CAPSULE
$8.0386
per EA
—
APTENSIO XR 30 MG CAPSULE
$8.0315
per EA
—
APTENSIO XR 10 MG CAPSULE
$8.0066
per EA
—
APTENSIO XR 50 MG CAPSULE
$7.9978
per EA
—
APTENSIO XR 20 MG CAPSULE
$7.9968
per EA
—
APTENSIO XR 15 MG CAPSULE
$7.9647
per EA
—
APTENSIO XR 40 MG CAPSULE
$7.9434
per EA
—
METHYLPHENIDATE ER 20 MG CAP
$5.9068
per EA
—
METHYLPHENIDATE ER 20 MG CAP
$5.9068
per EA
—
METHYLPHENIDATE ER 60 MG CAP
$5.8406
per EA
—
METHYLPHENIDATE ER 60 MG CAP
$5.8406
per EA
—
QUILLIVANT XR 25 MG/5 ML SUSP
$5.3962
per ML
0.00%
METHYLPHENIDATE ER 50 MG CAP
$4.4474
per EA
—
METHYLPHENIDATE ER 50 MG CAP
$4.4474
per EA
—
METHYLPHENIDATE ER 40 MG CAP
$4.2291
per EA
—
METHYLPHENIDATE ER 40 MG CAP
$4.2291
per EA
—
METHYLPHENIDATE ER 10 MG CAP
$3.5021
per EA
—
METHYLPHENIDATE ER 10 MG CAP
$3.5021
per EA
—
METHYLPHENIDATE 10 MG CHEW TAB
$3.1731
per EA
—
METHYLPHENIDATE 10 MG CHEW TAB
$2.9538
per EA
-2.07%
METHYLPHENIDATE 10 MG CHEW TAB
$2.9538
per EA
-2.07%
METHYLPHENIDATE ER 30 MG CAP
$2.8775
per EA
—
METHYLPHENIDATE ER 30 MG CAP
$2.8775
per EA
—
QUILLIVANT XR 25 MG/5 ML SUSP
$2.7009
per ML
-0.02%
METHYLPHENIDATE ER 15 MG CAP
$2.6482
per EA
—
METHYLPHENIDATE ER 15 MG CAP
$2.6482
per EA
—
METHYLPHENIDATE ER(LA) 10 MG CP
$2.3999
per EA
+4.18%
METHYLPHENIDATE ER(LA) 10 MG CP
$2.3999
per EA
+4.18%
QUILLIVANT XR 25 MG/5 ML SUSP
$2.1612
per ML
0.00%
METHYLPHENIDATE ER(LA) 40 MG CP
$2.0776
per EA
—
METHYLPHENIDATE 5 MG CHEW TAB
$2.0569
per EA
—
METHYLPHENIDATE ER(LA) 30 MG CP
$2.0275
per EA
—
METHYLPHENIDATE 5 MG CHEW TAB
$2.0092
per EA
+4.62%
METHYLPHENIDATE 5 MG CHEW TAB
$2.0092
per EA
+4.62%
METHYLPHENIDATE ER(LA) 30 MG CP
$1.9037
per EA
-6.11%
METHYLPHENIDATE ER(LA) 30 MG CP
$1.9037
per EA
-6.11%
METHYLPHENIDATE ER(LA) 30 MG CP
$1.9037
per EA
-6.11%
METHYLPHENIDATE ER(LA) 40 MG CP
$1.8537
per EA
-10.77%
METHYLPHENIDATE ER(LA) 40 MG CP
$1.8537
per EA
-10.77%
METHYLPHENIDATE ER(LA) 40 MG CP
$1.8537
per EA
-10.77%
METHYLPHENIDATE ER(CD) 60 MG CP
$1.8017
per EA
+2.05%
METHYLPHENIDATE ER(CD) 60 MG CP
$1.8017
per EA
+2.05%
METHYLPHENIDATE CD 60 MG CAP
$1.8017
per EA
+2.05%
QUILLIVANT XR 25 MG/5 ML SUSP
$1.8006
per ML
-0.14%
METHYLPHENIDATE ER(CD) 30 MG CP
$1.7946
per EA
-5.47%
METHYLPHENIDATE ER(CD) 30 MG CP
$1.7946
per EA
-5.47%
METHYLPHENIDATE CD 30 MG CAP
$1.7946
per EA
-5.47%
METHYLPHENIDATE ER(LA) 20 MG CP
$1.6954
per EA
-6.45%
METHYLPHENIDATE ER(LA) 20 MG CP
$1.6954
per EA
-6.45%
METHYLPHENIDATE ER(LA) 20 MG CP
$1.6954
per EA
-6.45%
RITALIN 20 MG TABLET
$1.6333
per EA
+0.02%
RITALIN 20 MG TABLET
$1.6330
per EA
—
METHYLPHENIDATE CD 50 MG CAP
$1.5726
per EA
+7.59%
METHYLPHENIDATE ER(CD) 50 MG CP
$1.5726
per EA
+7.59%
METHYLPHENIDATE ER(CD) 50 MG CP
$1.5726
per EA
+7.59%
METHYLPHENIDATE 2.5 MG CHEW TB
$1.5339
per EA
—
METHYLPHENIDATE ER(CD) 40 MG CP
$1.4414
per EA
+4.20%
METHYLPHENIDATE CD 40 MG CAP
$1.4414
per EA
+4.20%
METHYLPHENIDATE ER(CD) 40 MG CP
$1.4414
per EA
+4.20%
METHYLPHENIDATE CD 10 MG CAP
$1.4010
per EA
+10.34%
METHYLPHENIDATE ER(CD) 10 MG CP
$1.4010
per EA
+10.34%
METHYLPHENIDATE ER(CD) 10 MG CP
$1.4010
per EA
+10.34%
METHYLPHENIDATE ER(CD) 20 MG CP
$1.3876
per EA
-4.91%
METHYLPHENIDATE CD 20 MG CAP
$1.3876
per EA
-4.91%
METHYLPHENIDATE ER(CD) 20 MG CP
$1.3876
per EA
-4.91%
METHYLPHENIDATE 2.5 MG CHEW TB
$1.2991
per EA
+1.27%
METHYLPHENIDATE 2.5 MG CHEW TB
$1.2991
per EA
+1.27%
RITALIN 10 MG TABLET
$1.1344
per EA
+0.15%
RITALIN 10 MG TABLET
$1.1332
per EA
—
METHYLPHENIDATE 20 MG TABLET
$0.8991
per EA
—
METHYLPHENIDATE ER 27 MG TAB
$0.8554
per EA
—
METHYLPHENIDATE ER 54 MG TAB
$0.8329
per EA
—
METHYLPHENIDATE ER 54 MG TAB
$0.8092
per EA
—
METHYLPHENIDATE ER 54 MG TAB
$0.8051
per EA
-0.51%
METHYLPHENIDATE ER 54 MG TAB
$0.8051
per EA
-0.51%
METHYLPHENIDATE ER 54 MG TAB
$0.8051
per EA
-0.51%
METHYLPHENIDATE ER 54 MG TAB
$0.8051
per EA
-0.51%
METHYLPHENIDATE ER 54 MG TAB
$0.8051
per EA
-0.51%
METHYLPHENIDATE ER 54 MG TAB
$0.8051
per EA
-0.51%
RITALIN 5 MG TABLET
$0.7953
per EA
—
RITALIN 5 MG TABLET
$0.7935
per EA
+0.12%
METHYLPHENIDATE ER 36 MG TAB
$0.7332
per EA
—
METHYLPHENIDATE ER 27 MG TAB
$0.6766
per EA
+4.97%
METHYLPHENIDATE ER 27 MG TAB
$0.6766
per EA
+4.97%
METHYLPHENIDATE ER 27 MG TAB
$0.6766
per EA
+4.97%
METHYLPHENIDATE ER 27 MG TAB
$0.6766
per EA
+4.97%
METHYLPHENIDATE ER 27 MG TAB
$0.6766
per EA
+4.97%
METHYLPHENIDATE ER 27 MG TAB
$0.6766
per EA
+4.97%
METHYLPHENIDATE ER 36 MG TAB
$0.6715
per EA
+0.75%
METHYLPHENIDATE ER 36 MG TAB
$0.6715
per EA
+0.75%
METHYLPHENIDATE ER 36 MG TAB
$0.6715
per EA
+0.75%
METHYLPHENIDATE ER 36 MG TAB
$0.6715
per EA
+0.75%
METHYLPHENIDATE ER 36 MG TAB
$0.6715
per EA
+0.75%
METHYLPHENIDATE ER 36 MG TAB
$0.6715
per EA
+0.75%
METHYLPHENIDATE ER 36 MG TAB
$0.6715
per EA
+0.75%
METHYLPHENIDATE ER 36 MG TAB
$0.6665
per EA
—
METHYLPHENIDATE ER 18 MG TAB
$0.6645
per EA
—
METHYLPHENIDATE ER 27 MG TAB
$0.6446
per EA
—
METHYLPHENIDATE 10 MG TABLET
$0.6198
per EA
—
METHYLPHENIDATE ER 18 MG TAB
$0.5761
per EA
+0.05%
METHYLPHENIDATE ER 18 MG TAB
$0.5761
per EA
+0.05%
METHYLPHENIDATE ER 18 MG TAB
$0.5761
per EA
+0.05%
METHYLPHENIDATE ER 18 MG TAB
$0.5761
per EA
+0.05%
METHYLPHENIDATE ER 18 MG TAB
$0.5761
per EA
+0.05%
METHYLPHENIDATE ER 18 MG TAB
$0.5758
per EA
—
METHYLPHENIDATE ER 20 MG TAB
$0.5131
per EA
+0.24%
METHYLPHENIDATE ER 20 MG TAB
$0.5131
per EA
+0.24%
METHYLPHENIDATE ER 10 MG TAB
$0.4583
per EA
+4.78%
METHYLPHENIDATE ER 10 MG TAB
$0.4583
per EA
+4.78%
METHYLPHENIDATE 5 MG TABLET
$0.4169
per EA
—
METHYLIN 10 MG/5 ML SOLUTION
$0.2309
per ML
—
METHYLPHENIDATE 20 MG TABLET
$0.2014
per EA
-4.17%
METHYLPHENIDATE 20 MG TABLET
$0.2014
per EA
-4.17%
METHYLPHENIDATE 20 MG TABLET
$0.2014
per EA
-4.17%
METHYLPHENIDATE 20 MG TABLET
$0.2014
per EA
-4.17%
METHYLPHENIDATE 20 MG TABLET
$0.2014
per EA
-4.17%
METHYLPHENIDATE 20 MG TABLET
$0.2014
per EA
-4.17%
METHYLPHENIDATE 20 MG TABLET
$0.2014
per EA
-4.17%
METHYLPHENIDATE 20 MG TABLET
$0.2014
per EA
-4.17%
METHYLPHENIDATE 20 MG TABLET
$0.2014
per EA
-4.17%
METHYLPHENIDATE 20 MG TABLET
$0.2014
per EA
-4.17%
METHYLPHENIDATE 10 MG/5 ML SOL
$0.1984
per ML
—
METHYLPHENIDATE 10 MG TABLET
$0.1668
per EA
—
METHYLIN 5 MG/5 ML SOLUTION
$0.1616
per ML
+0.01%
METHYLPHENIDATE 10 MG TABLET
$0.1580
per EA
-5.29%
METHYLPHENIDATE 10 MG TABLET
$0.1580
per EA
-5.29%
METHYLPHENIDATE 10 MG TABLET
$0.1580
per EA
-5.29%
METHYLPHENIDATE 10 MG TABLET
$0.1580
per EA
-5.29%
METHYLPHENIDATE 10 MG TABLET
$0.1580
per EA
-5.29%
METHYLPHENIDATE 10 MG TABLET
$0.1580
per EA
-5.29%
METHYLPHENIDATE 10 MG TABLET
$0.1580
per EA
-5.29%
METHYLPHENIDATE 10 MG TABLET
$0.1580
per EA
-5.29%
METHYLPHENIDATE 10 MG TABLET
$0.1580
per EA
-5.29%
METHYLPHENIDATE 10 MG TABLET
$0.1580
per EA
-5.29%
METHYLPHENIDATE 20 MG TABLET
$0.1389
per EA
—
METHYLPHENIDATE 10 MG TABLET
$0.1374
per EA
—
METHYLPHENIDATE 5 MG TABLET
$0.1268
per EA
-3.10%
METHYLPHENIDATE 5 MG TABLET
$0.1268
per EA
-3.10%
METHYLPHENIDATE 5 MG TABLET
$0.1268
per EA
-3.10%
METHYLPHENIDATE 5 MG TABLET
$0.1268
per EA
-3.10%
METHYLPHENIDATE 5 MG TABLET
$0.1268
per EA
-3.10%
METHYLPHENIDATE 5 MG TABLET
$0.1268
per EA
-3.10%
METHYLPHENIDATE 5 MG TABLET
$0.1268
per EA
-3.10%
METHYLPHENIDATE 5 MG TABLET
$0.1268
per EA
-3.10%
METHYLPHENIDATE 5 MG TABLET
$0.1268
per EA
-3.10%
METHYLPHENIDATE 5 MG TABLET
$0.1268
per EA
-3.10%
METHYLPHENIDATE 5 MG/5 ML SOLN
$0.1230
per ML
—
METHYLPHENIDATE 5 MG/5 ML SOLN
$0.1208
per ML
—
METHYLPHENIDATE 10 MG/5 ML SOL
$0.1199
per ML
+0.83%
METHYLPHENIDATE 10 MG/5 ML SOL
$0.1199
per ML
+0.83%
METHYLPHENIDATE 10 MG/5 ML SOL
$0.1199
per ML
+0.83%
METHYLPHENIDATE 10 MG/5 ML SOL
$0.1133
per ML
—
METHYLPHENIDATE 5 MG TABLET
$0.0858
per EA
—
METHYLPHENIDATE 5 MG/5 ML SOLN
$0.0782
per ML
-0.18%
METHYLPHENIDATE 5 MG/5 ML SOLN
$0.0782
per ML
-0.18%
METHYLPHENIDATE 5 MG/5 ML SOLN
$0.0782
per ML
-0.18%

Frequently Asked Questions

What is Methylphenidate Hydrochloride used to treat?

Methylphenidate Hydrochloride is used to treat attention deficit disorder with hyperactivity, depressive disorder and narcolepsy, per the National Library of Medicine's MED-RT classification.

When did Methylphenidate Hydrochloride become available as a generic?

FDA approved the first generic Methylphenidate Hydrochloride (ANDA) on Jan 1, 1982. The Orange Book currently lists 135 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

Is Methylphenidate Hydrochloride in shortage?

Yes — FDA's drug shortage database currently lists 34 Methylphenidate Hydrochloride presentations with status "Current", first posted Jul 26, 2023.

How many Methylphenidate Hydrochloride products are on the market?

The Methylphenidate Hydrochloride drug market contains 187 NDCs from 32 manufacturers — 145 generic and 42 brand products.

What is the price range for Methylphenidate Hydrochloride?

NADAC reference prices for Methylphenidate Hydrochloride range from $0.0858 to $21.3526 per EA — the most expensive product costs about 249× the cheapest. 16 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Is generic Methylphenidate Hydrochloride cheaper than brand?

The average generic NADAC for Methylphenidate Hydrochloride is $2.1230 per EA, versus $10.2858 for brand-labeled products — brand versions average about 4.8× the generic price.

Which manufacturers make Methylphenidate Hydrochloride?

32 manufacturers list Methylphenidate Hydrochloride in NADAC. Ranked by number of NDCs, the largest are SpecGx LLC (17), Rhodes Pharmaceuticals L.P. (14), Actavis Pharma, Inc. (11), Camber Pharmaceuticals Inc. (10), Lannett Company Inc. (10).

How has the price of Methylphenidate Hydrochloride changed recently?

Over the past 7 days, 50 Methylphenidate Hydrochloride NDCs rose and 78 fell, with a market-wide average change of -0.8%.