Product Information

DOXYCYCLINE HYC DR 50 MG TAB is a generic product labeled by Solco Healthcare US LLC, priced at $1.5694 per EA under NDC 43547046212. Its NADAC has been published 175 times since May 19, 2021.

FDA first approved this application on Nov 15, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DOXYCYCLINE HYC DR 50 MG TAB

DOXYCYCLINE HYCLATE
$1.5694per EA

Strength

50 mg/1

NDC

43547046212

Classification

Generic

Dosage Form

TABLET, DELAYED RELEASE

Route

ORAL

Effective Date

4/22/2026

Active Ingredients

DOXYCYCLINE HYCLATE

Approval Type

Generic (ANDA)

FDA Application

ANDA207494

FDA Approved

11/15/2016

TE Code

AB

On Market Since

11/28/2018

Pharmacological Classes

Price Statistics

The NADAC for DOXYCYCLINE HYC DR 50 MG TAB has been published 175 times since May 19, 2021, and over the history we have for it it has declined 78.0%. The table below summarizes its recorded NADAC range and movement.

Current price$1.5694 per EA
All-time high$7.1248 (May 11, 2022)
All-time low$1.3741 (Dec 17, 2025)
52-week high$2.4192
52-week low$1.3741
Median price$2.4192
Average price$3.7069
Largest weekly change-53.1% (Apr 17, 2024)
Weeks tracked175
Tracking sinceMay 19, 2021

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

+6.6%

1Y

-35.1%

3Y

-78.0%

5Y

-78.0%

All

-78.0%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the DOXYCYCLINE HYCLATE market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of DOXYCYCLINE HYC DR 50 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for DOXYCYCLINE HYC DR 50 MG TAB, manufactured by Solco Healthcare US LLC, is $1.5694 per EA (NDC 43547046212), effective Aug 19, 2026.

How has the price of DOXYCYCLINE HYC DR 50 MG TAB changed over time?

Over the history we have for it, the NADAC for DOXYCYCLINE HYC DR 50 MG TAB has declined 78.0%. It has been tracked across 175 weekly CMS publications since May 19, 2021.

What are the highest and lowest recorded NADAC prices for DOXYCYCLINE HYC DR 50 MG TAB?

Since May 19, 2021, the NADAC for DOXYCYCLINE HYC DR 50 MG TAB has ranged from a low of $1.3741 (Dec 17, 2025) to a high of $7.1248 (May 11, 2022), with a median of $2.4192 per EA.

Are there cheaper alternatives to DOXYCYCLINE HYC DR 50 MG TAB?

No other NADAC-published product currently shares the active ingredient and strength of DOXYCYCLINE HYC DR 50 MG TAB in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures DOXYCYCLINE HYC DR 50 MG TAB?

DOXYCYCLINE HYC DR 50 MG TAB (NDC 43547046212) is labeled by Solco Healthcare US LLC, and CMS classifies it as a generic product.