Product Information
ACYCLOVIR 5% CREAM is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $10.2586 per GM under NDC 45802004475. Its NADAC has been published 345 times since Nov 20, 2019.
The High Outlier badge above means this manufacturer's average price in the Acyclovir market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 mg/g
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802004475
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
ACYCLOVIRApproval Type
Generic (ANDA)
FDA Application
ANDA208702On Market Since
2/11/2019
Pharmacological Classes
Price Statistics
The NADAC for ACYCLOVIR 5% CREAM has been published 345 times since Nov 20, 2019, and over the history we have for it it has declined 92.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $10.2586 per GM |
|---|---|
| All-time high | $144.8933 (Jan 15, 2020) |
| All-time low | $7.9189 (Nov 20, 2024) |
| 52-week high | $12.2143 |
| 52-week low | $9.2050 |
| Median price | $38.1209 |
| Average price | $53.6312 |
| Largest weekly change | +94.9% (Sep 22, 2021) |
| Weeks tracked | 345 |
| Tracking since | Nov 20, 2019 |
Generic Alternatives
The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 97% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ACYCLOVIR 5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for ACYCLOVIR 5% CREAM, manufactured by Padagis Israel Pharmaceuticals Ltd, is $10.2586 per GM (NDC 45802004475), effective Jun 24, 2026.
How has the price of ACYCLOVIR 5% CREAM changed over time?
Over the history we have for it, the NADAC for ACYCLOVIR 5% CREAM has declined 92.9%. It has been tracked across 345 weekly CMS publications since Nov 20, 2019.
What are the highest and lowest recorded NADAC prices for ACYCLOVIR 5% CREAM?
Since Nov 20, 2019, the NADAC for ACYCLOVIR 5% CREAM has ranged from a low of $7.9189 (Nov 20, 2024) to a high of $144.8933 (Jan 15, 2020), with a median of $38.1209 per GM.
Are there cheaper alternatives to ACYCLOVIR 5% CREAM?
Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, ACYCLOVIR 5% OINTMENT, is $0.3149 per GM — about 97% below ACYCLOVIR 5% CREAM.
Who manufactures ACYCLOVIR 5% CREAM?
ACYCLOVIR 5% CREAM (NDC 45802004475) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.
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