Product Information
MESALAMINE 4 GM/60 ML ENEMA is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $0.0984 per ML under NDC 45802009851. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Sep 17, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Mesalamine market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
4 g/60mL
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802009851
Classification
Generic
Dosage Form
ENEMA
Route
RECTAL
Effective Date
9/23/2026
Active Ingredients
MESALAMINEApproval Type
Generic (ANDA)
FDA Application
ANDA076751FDA Approved
9/17/2004
TE Code
AB
On Market Since
10/11/2007
Pharmacological Classes
Price Statistics
The NADAC for MESALAMINE 4 GM/60 ML ENEMA has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 49.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0984 per ML |
|---|---|
| All-time high | $0.2447 (Jun 15, 2016) |
| All-time low | $0.0870 (Jul 17, 2024) |
| 52-week high | $0.1209 |
| 52-week low | $0.0974 |
| Median price | $0.1665 |
| Average price | $0.1657 |
| Largest weekly change | -35.5% (Jul 17, 2024) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Padagis Israel Pharmaceuticals Ltd manufacturer profile
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Drug market
Mesalamine market comparison
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Therapeutic class
Aminosalicylate class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of MESALAMINE 4 GM/60 ML ENEMA?
The current National Average Drug Acquisition Cost (NADAC) for MESALAMINE 4 GM/60 ML ENEMA, manufactured by Padagis Israel Pharmaceuticals Ltd, is $0.0984 per ML (NDC 45802009851), effective Sep 30, 2026.
How has the price of MESALAMINE 4 GM/60 ML ENEMA changed over time?
Over the history we have for it, the NADAC for MESALAMINE 4 GM/60 ML ENEMA has declined 49.5%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for MESALAMINE 4 GM/60 ML ENEMA?
Since Nov 28, 2013, the NADAC for MESALAMINE 4 GM/60 ML ENEMA has ranged from a low of $0.0870 (Jul 17, 2024) to a high of $0.2447 (Jun 15, 2016), with a median of $0.1665 per ML.
Are there cheaper alternatives to MESALAMINE 4 GM/60 ML ENEMA?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as MESALAMINE 4 GM/60 ML ENEMA in a comparable dosage form, but none are currently priced below it.
Who manufactures MESALAMINE 4 GM/60 ML ENEMA?
MESALAMINE 4 GM/60 ML ENEMA (NDC 45802009851) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.