Product Information
MESALAMINE 4 GM/60 ML ENEMA is a generic product labeled by Encube Ethicals, Inc., priced at $0.0974 per ML under NDC 21922004547. Its NADAC has been published 118 times since May 22, 2024.
FDA first approved this application on May 30, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
4 g/60mL
Manufacturer
Encube Ethicals, Inc.NDC
21922004547
Classification
Generic
Dosage Form
SUSPENSION
Route
RECTAL
Effective Date
8/19/2026
Active Ingredients
MESALAMINEApproval Type
Generic (ANDA)
FDA Application
ANDA216941FDA Approved
5/30/2023
TE Code
AB
On Market Since
6/1/2023
Pharmacological Classes
Price Statistics
The NADAC for MESALAMINE 4 GM/60 ML ENEMA has been published 118 times since May 22, 2024, and over the history we have for it it has declined 24.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0974 per ML |
|---|---|
| All-time high | $0.1349 (Jul 10, 2024) |
| All-time low | $0.0870 (Jul 17, 2024) |
| 52-week high | $0.1209 |
| 52-week low | $0.0974 |
| Median price | $0.1168 |
| Average price | $0.1142 |
| Largest weekly change | -35.5% (Jul 17, 2024) |
| Weeks tracked | 118 |
| Tracking since | May 22, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MESALAMINE 4 GM/60 ML ENEMA?
The current National Average Drug Acquisition Cost (NADAC) for MESALAMINE 4 GM/60 ML ENEMA, manufactured by Encube Ethicals, Inc., is $0.0974 per ML (NDC 21922004547), effective Aug 19, 2026.
How has the price of MESALAMINE 4 GM/60 ML ENEMA changed over time?
Over the history we have for it, the NADAC for MESALAMINE 4 GM/60 ML ENEMA has declined 24.3%. It has been tracked across 118 weekly CMS publications since May 22, 2024.
What are the highest and lowest recorded NADAC prices for MESALAMINE 4 GM/60 ML ENEMA?
Since May 22, 2024, the NADAC for MESALAMINE 4 GM/60 ML ENEMA has ranged from a low of $0.0870 (Jul 17, 2024) to a high of $0.1349 (Jul 10, 2024), with a median of $0.1168 per ML.
Are there cheaper alternatives to MESALAMINE 4 GM/60 ML ENEMA?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as MESALAMINE 4 GM/60 ML ENEMA in a comparable dosage form, but none are currently priced below it.
Who manufactures MESALAMINE 4 GM/60 ML ENEMA?
MESALAMINE 4 GM/60 ML ENEMA (NDC 21922004547) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.