Product Information

MESALAMINE 4 GM/60 ML ENEMA is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $0.1789 per ML under NDC 45802009828. Its NADAC has been published 435 times since Nov 28, 2013.

FDA first approved this application on Sep 17, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Mesalamine market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

MESALAMINE 4 GM/60 ML ENEMA

Mesalamine
$0.1789per ML
High Outlier

Strength

4 g/60mL

NDC

45802009828

Classification

Generic

Dosage Form

ENEMA

Route

RECTAL

Effective Date

8/19/2026

Active Ingredients

MESALAMINE

Approval Type

Generic (ANDA)

FDA Application

ANDA076751

FDA Approved

9/17/2004

TE Code

AB

On Market Since

10/11/2007

Pharmacological Classes

Aminosalicylate
Aminosalicylic Acids

Price Statistics

The NADAC for MESALAMINE 4 GM/60 ML ENEMA has been published 435 times since Nov 28, 2013, and over the history we have for it it has declined 16.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1789 per ML
All-time high$0.2411 (Sep 14, 2016)
All-time low$0.1662 (Jan 21, 2026)
52-week high$0.1839
52-week low$0.1662
Median price$0.1868
Average price$0.1896
Largest weekly change+29.2% (Aug 17, 2016)
Weeks tracked435
Tracking sinceNov 28, 2013

Price History

1W

-1.4%

1M

-1.4%

3M

-2.7%

6M

+4.4%

1Y

-1.3%

3Y

-4.2%

5Y

-4.2%

All

-16.4%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 46% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of MESALAMINE 4 GM/60 ML ENEMA?

The current National Average Drug Acquisition Cost (NADAC) for MESALAMINE 4 GM/60 ML ENEMA, manufactured by Padagis Israel Pharmaceuticals Ltd, is $0.1789 per ML (NDC 45802009828), effective Aug 19, 2026.

How has the price of MESALAMINE 4 GM/60 ML ENEMA changed over time?

Over the history we have for it, the NADAC for MESALAMINE 4 GM/60 ML ENEMA has declined 16.4%. It has been tracked across 435 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for MESALAMINE 4 GM/60 ML ENEMA?

Since Nov 28, 2013, the NADAC for MESALAMINE 4 GM/60 ML ENEMA has ranged from a low of $0.1662 (Jan 21, 2026) to a high of $0.2411 (Sep 14, 2016), with a median of $0.1868 per ML.

Are there cheaper alternatives to MESALAMINE 4 GM/60 ML ENEMA?

Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, MESALAMINE 4 GM/60 ML ENEMA, is $0.0974 per ML — about 46% below MESALAMINE 4 GM/60 ML ENEMA.

Who manufactures MESALAMINE 4 GM/60 ML ENEMA?

MESALAMINE 4 GM/60 ML ENEMA (NDC 45802009828) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.