Product Information
MESALAMINE 4 GM/60 ML ENEMA is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $0.1789 per ML under NDC 45802009828. Its NADAC has been published 435 times since Nov 28, 2013.
FDA first approved this application on Sep 17, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Mesalamine market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
4 g/60mL
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802009828
Classification
Generic
Dosage Form
ENEMA
Route
RECTAL
Effective Date
8/19/2026
Active Ingredients
MESALAMINEApproval Type
Generic (ANDA)
FDA Application
ANDA076751FDA Approved
9/17/2004
TE Code
AB
On Market Since
10/11/2007
Pharmacological Classes
Price Statistics
The NADAC for MESALAMINE 4 GM/60 ML ENEMA has been published 435 times since Nov 28, 2013, and over the history we have for it it has declined 16.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1789 per ML |
|---|---|
| All-time high | $0.2411 (Sep 14, 2016) |
| All-time low | $0.1662 (Jan 21, 2026) |
| 52-week high | $0.1839 |
| 52-week low | $0.1662 |
| Median price | $0.1868 |
| Average price | $0.1896 |
| Largest weekly change | +29.2% (Aug 17, 2016) |
| Weeks tracked | 435 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 46% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MESALAMINE 4 GM/60 ML ENEMA?
The current National Average Drug Acquisition Cost (NADAC) for MESALAMINE 4 GM/60 ML ENEMA, manufactured by Padagis Israel Pharmaceuticals Ltd, is $0.1789 per ML (NDC 45802009828), effective Aug 19, 2026.
How has the price of MESALAMINE 4 GM/60 ML ENEMA changed over time?
Over the history we have for it, the NADAC for MESALAMINE 4 GM/60 ML ENEMA has declined 16.4%. It has been tracked across 435 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for MESALAMINE 4 GM/60 ML ENEMA?
Since Nov 28, 2013, the NADAC for MESALAMINE 4 GM/60 ML ENEMA has ranged from a low of $0.1662 (Jan 21, 2026) to a high of $0.2411 (Sep 14, 2016), with a median of $0.1868 per ML.
Are there cheaper alternatives to MESALAMINE 4 GM/60 ML ENEMA?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, MESALAMINE 4 GM/60 ML ENEMA, is $0.0974 per ML — about 46% below MESALAMINE 4 GM/60 ML ENEMA.
Who manufactures MESALAMINE 4 GM/60 ML ENEMA?
MESALAMINE 4 GM/60 ML ENEMA (NDC 45802009828) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.