Product Information

ONDANSETRON HCL 4 MG TABLET is a generic product labeled by Actavis Pharma, Inc., priced at $0.0633 per EA under NDC 45963053830. Its NADAC has been published 649 times since Nov 28, 2013.

FDA first approved this application on Jun 25, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ONDANSETRON HCL 4 MG TABLET

Ondansetron
$0.0633per EA
Discontinued

Strength

4 mg/1

NDC

45963053830

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

4/22/2026

Active Ingredients

ONDANSETRON HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA077851

FDA Approved

6/25/2007

TE Code

AB

On Market Since

7/27/2007

Pharmacological Classes

Serotonin 3 Receptor Antagonists
Serotonin-3 Receptor Antagonist

Price Statistics

The NADAC for ONDANSETRON HCL 4 MG TABLET has been published 649 times since Nov 28, 2013, and over the history we have for it it has declined 48.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0633 per EA
All-time high$0.3426 (May 14, 2014)
All-time low$0.0555 (Jul 17, 2024)
52-week high$0.0693
52-week low$0.0633
Median price$0.0831
Average price$0.1140
Largest weekly change+88.2% (Jan 22, 2014)
Weeks tracked649
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

N/A

6M

-2.6%

1Y

-8.6%

3Y

-9.7%

5Y

-25.3%

All

-48.5%

Last surveyed Apr 29, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 6% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ONDANSETRON HCL 4 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ONDANSETRON HCL 4 MG TABLET, manufactured by Actavis Pharma, Inc., is $0.0633 per EA (NDC 45963053830), effective Apr 29, 2026.

How has the price of ONDANSETRON HCL 4 MG TABLET changed over time?

Over the history we have for it, the NADAC for ONDANSETRON HCL 4 MG TABLET has declined 48.5%. It has been tracked across 649 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ONDANSETRON HCL 4 MG TABLET?

Since Nov 28, 2013, the NADAC for ONDANSETRON HCL 4 MG TABLET has ranged from a low of $0.0555 (Jul 17, 2024) to a high of $0.3426 (May 14, 2014), with a median of $0.0831 per EA.

Are there cheaper alternatives to ONDANSETRON HCL 4 MG TABLET?

Yes. 8 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ONDANSETRON HCL 4 MG TABLET, is $0.0597 per EA — about 6% below ONDANSETRON HCL 4 MG TABLET.

Who manufactures ONDANSETRON HCL 4 MG TABLET?

ONDANSETRON HCL 4 MG TABLET (NDC 45963053830) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.