Product Information
NASAL SPRAY ORIGINAL 0.05% is a generic product labeled by AmerisourceBergen, priced at $0.0763 per ML under NDC 46122016510. Its NADAC has been published 657 times since Nov 28, 2013.
Strength
.05 g/100mL
Manufacturer
AmerisourceBergenNDC
46122016510
Classification
Generic
Dosage Form
SPRAY
Route
NASAL
Last Updated
6/17/2026
Active Ingredients
OXYMETAZOLINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
1/15/1990
Pharmacological Classes
Price Statistics
The NADAC for NASAL SPRAY ORIGINAL 0.05% has been published 657 times since Nov 28, 2013, and over the history we have for it it has risen 42.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0763 per ML |
|---|---|
| All-time high | $0.0820 (Jul 12, 2023) |
| All-time low | $0.0503 (Sep 17, 2014) |
| 52-week high | $0.0778 |
| 52-week low | $0.0706 |
| Median price | $0.0595 |
| Average price | $0.0626 |
| Largest weekly change | +24.6% (Jan 18, 2023) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of NASAL SPRAY ORIGINAL 0.05%?
The current National Average Drug Acquisition Cost (NADAC) for NASAL SPRAY ORIGINAL 0.05%, manufactured by AmerisourceBergen, is $0.0763 per ML (NDC 46122016510), effective Jun 24, 2026.
How has the price of NASAL SPRAY ORIGINAL 0.05% changed over time?
Over the history we have for it, the NADAC for NASAL SPRAY ORIGINAL 0.05% has risen 42.2%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for NASAL SPRAY ORIGINAL 0.05%?
Since Nov 28, 2013, the NADAC for NASAL SPRAY ORIGINAL 0.05% has ranged from a low of $0.0503 (Sep 17, 2014) to a high of $0.0820 (Jul 12, 2023), with a median of $0.0595 per ML.
Are there cheaper alternatives to NASAL SPRAY ORIGINAL 0.05%?
Yes. 5 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, NASAL SPRAY 0.05%, is $0.0625 per ML — about 18% below NASAL SPRAY ORIGINAL 0.05%.
Who manufactures NASAL SPRAY ORIGINAL 0.05%?
NASAL SPRAY ORIGINAL 0.05% (NDC 46122016510) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.
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