Drug Markets/Oxymetazoline Hydrochloride

Oxymetazoline Hydrochloride

30 NDCs across 13 manufacturers|20 Generic,10 Brand

Oxymetazoline Hydrochloride is used to treat common cold, conjunctivitis, rhinitis and sinusitis, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on May 30, 1986, and the first generic was approved Oct 4, 2021. FDA's Orange Book lists 2 AB-rated (therapeutically equivalent) products for this ingredient.

Oxymetazoline Hydrochloride is available as 30 NDCs from 13 manufacturers (20 generic, 10 brand), with NADAC prices from $0.06 to $0.36 per ML — the most expensive product costs about 5.8× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

20G / 10B

Manufacturers

competing in market

Price Spread

$0.06 – $0.36

per ML, 28 of 30 NDCs

7d Activity

9↑5↓16 flat

avg -0.7% WoW · of 30 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

13 manufacturers producing OXYMETAZOLINE HYDROCHLORIDE(2 pricing outliers)

Chain Drug Marketing Association

4 NDCs

$0.1056

avg/unit

Strategic Sourcing Services LLC

Major Pharmaceuticals

Taro Pharmaceuticals U.S.A. Inc.

Padagis Israel Pharmaceuticals Ltd

1 NDC

$0.0757

avg/unit

Drug Portfolio

30 NDCs total, 30 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
RHOFADE 1% CREAM	51862076530	Mayne Pharma	$23.4789 per GM	High Outlier	Brand	+0.06%	Vasoconstrictor
RHOFADE 1% CREAM	71403000330	EPI Health, LLC	$22.5013 per GM	High Outlier	Brand	—	Vasoconstrictor
MUCINEX SINUS-MAX NASAL SPRAY	63824012011	RB Health (US) LLC	$0.3610 per ML	—	Brand OTC	—	Vasoconstrictor
MUCINEX SINUS-MAX NASAL SPRAY	63824012917	RB Health (US) LLC	$0.3610 per ML	—	Brand OTC	—	Vasoconstrictor
AFRIN NO DRIP PUMP MIST	11523178301	Bayer HealthCare LLC	$0.3443 per ML	—	Brand OTC	—	Vasoconstrictor
AFRIN NO DRIP ORIG PUMP MIST	11523314201	Bayer HealthCare LLC	$0.3443 per ML	—	Brand OTC	—	Vasoconstrictor
AFRIN 0.05% NASAL SPRAY	11523115901	Bayer HealthCare LLC	$0.3089 per ML	—	Brand OTC	—	Vasoconstrictor
AFRIN 0.05% NASAL SPRAY	11523116706	Bayer HealthCare LLC	$0.3089 per ML	—	Brand OTC	—	Vasoconstrictor
AFRIN 0.05% NASAL SPRAY	11523116703	Bayer HealthCare LLC	$0.3089 per ML	—	Brand OTC	—	Vasoconstrictor
AFRIN 0.05% NASAL SPRAY	11523116705	Bayer HealthCare LLC	$0.2247 per ML	—	Brand OTC	—	Vasoconstrictor
QC NO DRIP NASAL MIST 0.05%	63868060501	Chain Drug Marketing Association	$0.1370 per ML	—	Generic OTC	—	Vasoconstrictor
NASAL DECONGESTANT 0.05% SPRAY	00904743535	Major Pharmaceuticals	$0.1218 per ML	—	Generic OTC	+1.36%	Vasoconstrictor
QC NO DRIP NASAL MIST 0.05%	83324027401	Chain Drug Marketing Association	$0.1049 per ML	—	Generic OTC	-4.58%	Vasoconstrictor
QC NO DRIP NASAL MIST 0.05%	83324021101	Chain Drug Marketing Association	$0.1049 per ML	—	Generic OTC	-4.58%	Vasoconstrictor
FT NASAL SPRAY 0.05%	70677103901	Strategic Sourcing Services LLC	$0.1049 per ML	—	Generic OTC	-4.58%	Vasoconstrictor
NASAL DECONGESTANT 0.05% SPRAY	70000066501	Cardinal Health	$0.1049 per ML	—	Generic OTC	-4.58%	Vasoconstrictor
GNP NO DRIP NASAL MIST 0.05%	46122079235	AmerisourceBergen	$0.1049 per ML	—	Generic OTC	-4.58%	Vasoconstrictor
SM NASAL SPRAY 0.05%	49348002827	Strategic Sourcing Services LLC	$0.0763 per ML	—	Generic OTC	—	Vasoconstrictor
FT NASAL SPRAY 0.05%	70677103701	Strategic Sourcing Services LLC	$0.0757 per ML	—	Generic OTC	+1.61%	Vasoconstrictor
QC NASAL SPRAY 0.05%	83324023801	Chain Drug Marketing Association	$0.0757 per ML	—	Generic OTC	+1.61%	Vasoconstrictor
FT NASAL SPRAY 0.05%	70677104001	Strategic Sourcing Services LLC	$0.0757 per ML	—	Generic OTC	+1.61%	Vasoconstrictor
NASAL SPRAY ORIGINAL 0.05%	46122016510	AmerisourceBergen	$0.0757 per ML	—	Generic OTC	+1.61%	Vasoconstrictor
NASAL SPRAY 0.05%	45802041059	Padagis Israel Pharmaceuticals Ltd	$0.0757 per ML	—	Generic OTC	+1.61%	Vasoconstrictor
NASAL DECONGESTANT 0.05% SPRAY	00904742730	Major Pharmaceuticals	$0.0757 per ML	—	Generic OTC	+1.61%	Vasoconstrictor
GS NASAL SPRAY 0.05%	00113030410	L. Perrigo Company	$0.0757 per ML	—	Generic OTC	+1.61%	Vasoconstrictor
GS SINUS NASAL SPRAY 0.05%	00113081710	L. Perrigo Company	$0.0737 per ML	—	Generic OTC	—	Vasoconstrictor
NASAL DECONGESTANT 0.05% SPRAY	51672203003	Taro Pharmaceuticals U.S.A. Inc.	$0.0678 per ML	—	Generic OTC	—	Vasoconstrictor
NASAL DECONGESTANT 0.05% SPRAY	51672203005	Taro Pharmaceuticals U.S.A. Inc.	$0.0625 per ML	—	Generic OTC	—	Vasoconstrictor
NASAL SPRAY 0.05%	36800081710	Topco Associates LLC	$0.0625 per ML	—	Generic OTC	—	Vasoconstrictor
NASAL SPRAY 0.05%	36800030410	Topco Associates LLC	$0.0625 per ML	—	Generic OTC	—	Vasoconstrictor

Frequently Asked Questions

What is Oxymetazoline Hydrochloride used to treat?

Oxymetazoline Hydrochloride is used to treat common cold, conjunctivitis, rhinitis and sinusitis, per the National Library of Medicine's MED-RT classification.

When did Oxymetazoline Hydrochloride become available as a generic?

FDA approved the first generic Oxymetazoline Hydrochloride (ANDA) on Oct 4, 2021. The Orange Book currently lists 2 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How many Oxymetazoline Hydrochloride products are on the market?

The Oxymetazoline Hydrochloride drug market contains 30 NDCs from 13 manufacturers — 20 generic and 10 brand products.

What is the price range for Oxymetazoline Hydrochloride?

NADAC reference prices for Oxymetazoline Hydrochloride range from $0.0625 to $0.3610 per ML — the most expensive product costs about 5.8× the cheapest. 2 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Is generic Oxymetazoline Hydrochloride cheaper than brand?

The average generic NADAC for Oxymetazoline Hydrochloride is $0.0859 per ML, versus $0.3202 for brand-labeled products — brand versions average about 3.7× the generic price.

Which manufacturers make Oxymetazoline Hydrochloride?

13 manufacturers list Oxymetazoline Hydrochloride in NADAC. Ranked by number of NDCs, the largest are Bayer HealthCare LLC (6), Chain Drug Marketing Association (4), Strategic Sourcing Services LLC (4), RB Health (US) LLC (2), Major Pharmaceuticals (2).

How has the price of Oxymetazoline Hydrochloride changed recently?

Over the past 7 days, 9 Oxymetazoline Hydrochloride NDCs rose and 5 fell, with a market-wide average change of -0.7%.