Product Information

NAPROXEN SODIUM 220 MG CAPSULE is a generic product labeled by AmerisourceBergen, priced at $0.1489 per EA under NDC 46122053460. Its NADAC has been published 363 times since Jul 17, 2019.

NAPROXEN SODIUM 220 MG CAPSULE

Naproxen Sodium
$0.1489per EA
OTC

Strength

220 mg/1

Manufacturer

AmerisourceBergen

NDC

46122053460

Classification

Generic

Dosage Form

CAPSULE, LIQUID FILLED

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

NAPROXEN SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA208363

On Market Since

4/1/2018

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for NAPROXEN SODIUM 220 MG CAPSULE has been published 363 times since Jul 17, 2019, and over the history we have for it it has risen 3.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1489 per EA
All-time high$0.1734 (Dec 13, 2023)
All-time low$0.1331 (Jul 23, 2025)
52-week high$0.1489
52-week low$0.1331
Median price$0.1457
Average price$0.1466
Largest weekly change-12.1% (Dec 20, 2023)
Weeks tracked363
Tracking sinceJul 17, 2019

Price History

1W

0.0%

1M

+1.7%

3M

+3.3%

6M

+3.3%

1Y

+11.3%

3Y

-3.2%

5Y

+8.1%

All

+3.0%

Generic Alternatives

The matcher finds 7 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 7 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 63% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of NAPROXEN SODIUM 220 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN SODIUM 220 MG CAPSULE, manufactured by AmerisourceBergen, is $0.1489 per EA (NDC 46122053460), effective Jun 24, 2026.

How has the price of NAPROXEN SODIUM 220 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for NAPROXEN SODIUM 220 MG CAPSULE has risen 3.0%. It has been tracked across 363 weekly CMS publications since Jul 17, 2019.

What are the highest and lowest recorded NADAC prices for NAPROXEN SODIUM 220 MG CAPSULE?

Since Jul 17, 2019, the NADAC for NAPROXEN SODIUM 220 MG CAPSULE has ranged from a low of $0.1331 (Jul 23, 2025) to a high of $0.1734 (Dec 13, 2023), with a median of $0.1457 per EA.

Are there cheaper alternatives to NAPROXEN SODIUM 220 MG CAPSULE?

Yes. 7 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, ALL DAY PAIN RLF 220 MG CAPLET, is $0.0551 per EA — about 63% below NAPROXEN SODIUM 220 MG CAPSULE.

Who manufactures NAPROXEN SODIUM 220 MG CAPSULE?

NAPROXEN SODIUM 220 MG CAPSULE (NDC 46122053460) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.