Naproxen Sodium

65 NDCs across 18 manufacturers|63 Generic,2 Brand

Naproxen Sodium is used to treat juvenile arthritis, rheumatoid arthritis, back pain, bursitis, common cold and dysmenorrhea, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved before 1982, and the first generic was approved Aug 31, 1993. FDA's Orange Book lists 15 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $6 million on Naproxen Sodium across 74,000 claims for 40,000 beneficiaries.

Naproxen Sodium is available as 65 NDCs from 18 manufacturers (63 generic, 2 brand), with NADAC prices from $0.06 to $22.17 per EA — the most expensive product costs about 403× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

63G / 2B

Manufacturers

competing in market

Price Spread

$0.06 – $22.17

per EA

7d Activity

11↑40↓14 flat

avg -0.1% WoW · of 65 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

18 manufacturers producing NAPROXEN SODIUM(4 pricing outliers)

Chain Drug Marketing Association

Glenmark Pharmaceuticals Inc., USA

4 NDCs

$0.3197

avg/unit

ScieGen Pharmaceuticals, Inc.

4 NDCs

$0.2115

avg/unit

Strategic Sourcing Services LLC

Dr. Reddy's Laboratories Inc.

Aurobindo Pharma Limited

2 NDCs

$0.2115

avg/unit

Padagis Israel Pharmaceuticals Ltd

Upsher-Smith Laboratories LLC

Teva Pharmaceuticals USA Inc.

Drug Portfolio

65 NDCs total, 65 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
NAPRELAN CR 750 MG TABLET	52427027430	Almatica Pharma LLC	$22.1736 per EA	High Outlier	Brand	—	Nonsteroidal Anti-inflammatory Drug
NAPRELAN CR 375 MG TABLET	52427027201	Almatica Pharma LLC	$17.8402 per EA	High Outlier	Brand	—	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SOD CR 500 MG TABLET	24979025368	Upsher-Smith Laboratories LLC	$9.5851 per EA	High Outlier	Generic	-0.08%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SOD ER 500 MG TABLET	00480095258	Teva Pharmaceuticals USA Inc.	$9.5851 per EA	High Outlier	Generic	-0.08%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SOD CR 500 MG TABLET	47781015475	Alvogen Inc.	$9.5851 per EA	High Outlier	Generic	-0.08%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 275 MG TAB	68462017805	Glenmark Pharmaceuticals Inc., USA	$0.6297 per EA	—	Generic	—	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 550 MG TAB	43598049501	Dr. Reddy's Laboratories Inc.	$0.2330 per EA	—	Generic	+1.89%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 550 MG TAB	43598049505	Dr. Reddy's Laboratories Inc.	$0.2330 per EA	—	Generic	+1.89%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 550 MG TAB	50228043301	ScieGen Pharmaceuticals, Inc.	$0.2330 per EA	—	Generic	+1.89%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 550 MG TAB	50228043305	ScieGen Pharmaceuticals, Inc.	$0.2330 per EA	—	Generic	+1.89%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 550 MG TAB	65862051601	Aurobindo Pharma Limited	$0.2330 per EA	—	Generic	+1.89%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 550 MG TAB	68462017901	Glenmark Pharmaceuticals Inc., USA	$0.2330 per EA	—	Generic	+1.89%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 550 MG TAB	68462017905	Glenmark Pharmaceuticals Inc., USA	$0.2260 per EA	—	Generic	—	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 275 MG TAB	65862051501	Aurobindo Pharma Limited	$0.1900 per EA	—	Generic	+10.35%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 275 MG TAB	68462017801	Glenmark Pharmaceuticals Inc., USA	$0.1900 per EA	—	Generic	+10.35%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 275 MG TAB	43598049401	Dr. Reddy's Laboratories Inc.	$0.1900 per EA	—	Generic	+10.35%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 275 MG TAB	50228043201	ScieGen Pharmaceuticals, Inc.	$0.1900 per EA	—	Generic	+10.35%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 275 MG TAB	50228043205	ScieGen Pharmaceuticals, Inc.	$0.1900 per EA	—	Generic	+10.35%	Nonsteroidal Anti-inflammatory Drug
HM NAPROXEN SODIUM 220 MG CAP	62011036901	Strategic Sourcing Services LLC	$0.1549 per EA	—	Generic OTC	—	Nonsteroidal Anti-inflammatory Drug
FT NAPROXEN SODIUM 220 MG CAP	70677114801	Strategic Sourcing Services LLC	$0.1507 per EA	—	Generic OTC	-0.39%	Nonsteroidal Anti-inflammatory Drug
GNP NAPROXEN SODIUM 220 MG CAP	46122078064	AmerisourceBergen	$0.1507 per EA	—	Generic OTC	-0.39%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG CAPSULE	46122053460	AmerisourceBergen	$0.1507 per EA	—	Generic OTC	-0.39%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	69230032924	Camber Consumer Care	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	69230032950	Camber Consumer Care	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RELIEF 220 MG TAB	70000017103	Cardinal Health	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RELIEF 220 MG TAB	70000017105	Cardinal Health	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RELIEF 220 MG TAB	70000017106	Cardinal Health	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RLF 220 MG CAPLET	70000020102	Cardinal Health	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RLF 220 MG CAPLET	70000020105	Cardinal Health	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RLF 220 MG CAPLET	70000020106	Cardinal Health	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
FT ALL DAY PAIN 220 MG CAPLET	70677113701	Strategic Sourcing Services LLC	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
FT ALL DAY PAIN 220 MG CAPLET	70677113702	Strategic Sourcing Services LLC	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
QC NAPROXEN SOD 220 MG CAPLET	83324010850	Chain Drug Marketing Association	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
QC NAPROXEN SOD 220 MG TABLET	83324010950	Chain Drug Marketing Association	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
GNP NAPROXEN SOD 220 MG TABLET	46122056258	AmerisourceBergen	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
GS NAPROXEN SOD 220 MG TABLET	00113090175	L. Perrigo Company	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
GS NAPROXEN SOD 220 MG CAPLET	00113436862	L. Perrigo Company	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
GS NAPROXEN SOD 220 MG CAPLET	00113436875	L. Perrigo Company	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
GS NAPROXEN SOD 220 MG CAPLET	00113436879	L. Perrigo Company	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
ALL DAY RELIEF 220 MG CAPLET	00536109306	Rugby Laboratories	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
ALL DAY RELIEF 220 MG CAPLET	00536109311	Rugby Laboratories	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
ALL DAY RELIEF 220 MG TABLET	00536109406	Rugby Laboratories	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
ALL DAY RELIEF 220 MG TABLET	00536109411	Rugby Laboratories	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	45802049075	Padagis Israel Pharmaceuticals Ltd	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
GS NAPROXEN SOD 220 MG TABLET	00113090162	L. Perrigo Company	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
GNP NAPROXEN SOD 220 MG TABLET	46122056271	AmerisourceBergen	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	46122056278	AmerisourceBergen	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
GNP NAPROXEN SOD 220 MG CAPLET	46122056471	AmerisourceBergen	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
GNP NAPROXEN SOD 220 MG CAPLET	46122056478	AmerisourceBergen	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
GNP NAPROXEN SOD 220 MG CAPLET	46122056481	AmerisourceBergen	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	49483060901	Time-Cap Labs Inc.	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	49483060905	Time-Cap Labs Inc.	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	69230032901	Camber Consumer Care	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	69230032902	Camber Consumer Care	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	69230032905	Camber Consumer Care	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	69230032910	Camber Consumer Care	$0.0669 per EA	—	Generic OTC	-2.03%	Nonsteroidal Anti-inflammatory Drug
NAPROXEN SODIUM 220 MG TABLET	45802049071	Padagis Israel Pharmaceuticals Ltd	$0.0669 per EA	—	Generic OTC	—	Nonsteroidal Anti-inflammatory Drug
QC NAPROXEN SOD 220 MG CAPLET	63868046650	Chain Drug Marketing Association	$0.0644 per EA	—	Generic OTC	—	Nonsteroidal Anti-inflammatory Drug
QC NAPROXEN SOD 220 MG TABLET	63868046550	Chain Drug Marketing Association	$0.0644 per EA	—	Generic OTC	—	Nonsteroidal Anti-inflammatory Drug
QC NAPROXEN SOD 220 MG TABLET	63868046501	Chain Drug Marketing Association	$0.0644 per EA	—	Generic OTC	—	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RLF 220 MG CAPLET	36800036871	Topco Associates LLC	$0.0551 per EA	—	Generic OTC	—	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RLF 220 MG CAPLET	36800036862	Topco Associates LLC	$0.0551 per EA	—	Generic OTC	—	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RLF 220 MG CAPLET	36800036882	Topco Associates LLC	$0.0551 per EA	—	Generic OTC	—	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RELIEF 220 MG TAB	36800049062	Topco Associates LLC	$0.0551 per EA	—	Generic OTC	—	Nonsteroidal Anti-inflammatory Drug
ALL DAY PAIN RELIEF 220 MG TAB	36800049071	Topco Associates LLC	$0.0551 per EA	—	Generic OTC	—	Nonsteroidal Anti-inflammatory Drug

Frequently Asked Questions

What is Naproxen Sodium used to treat?

Naproxen Sodium is used to treat juvenile arthritis, rheumatoid arthritis, back pain, bursitis, common cold and dysmenorrhea, per the National Library of Medicine's MED-RT classification.

When did Naproxen Sodium become available as a generic?

FDA approved the first generic Naproxen Sodium (ANDA) on Aug 31, 1993. The Orange Book currently lists 15 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How much does Medicare spend on Naproxen Sodium?

In 2024, Medicare Part D spent $6 million on Naproxen Sodium across 74,000 claims for 40,000 beneficiaries.

How many Naproxen Sodium products are on the market?

The Naproxen Sodium drug market contains 65 NDCs from 18 manufacturers — 63 generic and 2 brand products.

What is the price range for Naproxen Sodium?

NADAC reference prices for Naproxen Sodium range from $0.0551 to $22.1736 per EA — the most expensive product costs about 403× the cheapest.

Is generic Naproxen Sodium cheaper than brand?

The average generic NADAC for Naproxen Sodium is $0.5615 per EA, versus $20.0069 for brand-labeled products — brand versions average about 36× the generic price.

Which manufacturers make Naproxen Sodium?

18 manufacturers list Naproxen Sodium in NADAC. Ranked by number of NDCs, the largest are AmerisourceBergen (8), Camber Consumer Care (6), Cardinal Health (6), Chain Drug Marketing Association (5), L. Perrigo Company (5).

How has the price of Naproxen Sodium changed recently?

Over the past 7 days, 11 Naproxen Sodium NDCs rose and 40 fell, with a market-wide average change of -0.1%.