Product Information

OMEPRAZOLE DR 20 MG ODT is a generic product labeled by AmerisourceBergen, priced at $0.4413 per EA under NDC 46122061604. Its NADAC has been published 197 times since Sep 21, 2022.

OMEPRAZOLE DR 20 MG ODT

omeprazole
$0.4413per EA
OTC

Strength

20 mg/1

Manufacturer

AmerisourceBergen

NDC

46122061604

Classification

Generic

Dosage Form

TABLET, ORALLY DISINTEGRATING, DELAYED RELEASE

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

OMEPRAZOLE

Approval Type

New Drug (NDA)

FDA Application

NDA209400

On Market Since

9/11/2019

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Proton Pump Inhibitor
Proton Pump Inhibitors

Price Statistics

The NADAC for OMEPRAZOLE DR 20 MG ODT has been published 197 times since Sep 21, 2022, and over the history we have for it it has risen 5.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4413 per EA
All-time high$0.5117 (Mar 13, 2024)
All-time low$0.3603 (Nov 22, 2023)
52-week high$0.4785
52-week low$0.4242
Median price$0.4147
Average price$0.4179
Largest weekly change-28.8% (Mar 20, 2024)
Weeks tracked197
Tracking sinceSep 21, 2022

Price History

1W

0.0%

1M

+4.0%

3M

-0.2%

6M

+1.9%

1Y

-1.4%

3Y

+4.5%

5Y

N/A

All

+5.6%

Generic Alternatives

The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 92% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of OMEPRAZOLE DR 20 MG ODT?

The current National Average Drug Acquisition Cost (NADAC) for OMEPRAZOLE DR 20 MG ODT, manufactured by AmerisourceBergen, is $0.4413 per EA (NDC 46122061604), effective Jun 24, 2026.

How has the price of OMEPRAZOLE DR 20 MG ODT changed over time?

Over the history we have for it, the NADAC for OMEPRAZOLE DR 20 MG ODT has risen 5.6%. It has been tracked across 197 weekly CMS publications since Sep 21, 2022.

What are the highest and lowest recorded NADAC prices for OMEPRAZOLE DR 20 MG ODT?

Since Sep 21, 2022, the NADAC for OMEPRAZOLE DR 20 MG ODT has ranged from a low of $0.3603 (Nov 22, 2023) to a high of $0.5117 (Mar 13, 2024), with a median of $0.4147 per EA.

Are there cheaper alternatives to OMEPRAZOLE DR 20 MG ODT?

Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, OMEPRAZOLE DR 20 MG CAPSULE, is $0.0337 per EA — about 92% below OMEPRAZOLE DR 20 MG ODT.

Who manufactures OMEPRAZOLE DR 20 MG ODT?

OMEPRAZOLE DR 20 MG ODT (NDC 46122061604) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.