Product Information
GNP ANTI-DIARRHEAL 2 MG TABLET is a generic product labeled by AmerisourceBergen, priced at $0.1299 per EA under NDC 46122073853. Its NADAC has been published 160 times since Sep 13, 2023.
FDA first approved this application on Dec 15, 2015.
Strength
2 mg/1
Manufacturer
AmerisourceBergenNDC
46122073853
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LOPERAMIDE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA206548FDA Approved
12/15/2015
On Market Since
7/5/2023
Pharmacological Classes
Price Statistics
The NADAC for GNP ANTI-DIARRHEAL 2 MG TABLET has been published 160 times since Sep 13, 2023, and over the history we have for it it has declined 4.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1299 per EA |
|---|---|
| All-time high | $0.1738 (Feb 14, 2024) |
| All-time low | $0.1233 (Apr 22, 2026) |
| 52-week high | $0.1465 |
| 52-week low | $0.1233 |
| Median price | $0.1356 |
| Average price | $0.1420 |
| Largest weekly change | +26.8% (Sep 20, 2023) |
| Weeks tracked | 160 |
| Tracking since | Sep 13, 2023 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 7% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
AmerisourceBergen manufacturer profile
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Drug market
Loperamide Hydrochloride market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GNP ANTI-DIARRHEAL 2 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GNP ANTI-DIARRHEAL 2 MG TABLET, manufactured by AmerisourceBergen, is $0.1299 per EA (NDC 46122073853), effective Sep 30, 2026.
How has the price of GNP ANTI-DIARRHEAL 2 MG TABLET changed over time?
Over the history we have for it, the NADAC for GNP ANTI-DIARRHEAL 2 MG TABLET has declined 4.7%. It has been tracked across 160 weekly CMS publications since Sep 13, 2023.
What are the highest and lowest recorded NADAC prices for GNP ANTI-DIARRHEAL 2 MG TABLET?
Since Sep 13, 2023, the NADAC for GNP ANTI-DIARRHEAL 2 MG TABLET has ranged from a low of $0.1233 (Apr 22, 2026) to a high of $0.1738 (Feb 14, 2024), with a median of $0.1356 per EA.
Are there cheaper alternatives to GNP ANTI-DIARRHEAL 2 MG TABLET?
Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, QC ANTI-DIARRHEAL 2 MG CAPLET, is $0.1204 per EA — about 7% below GNP ANTI-DIARRHEAL 2 MG TABLET.
Who manufactures GNP ANTI-DIARRHEAL 2 MG TABLET?
GNP ANTI-DIARRHEAL 2 MG TABLET (NDC 46122073853) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.