Product Information

GNP ANTI-DIARRHEAL 2 MG TABLET is a generic product labeled by AmerisourceBergen, priced at $0.1335 per EA under NDC 46122073862. Its NADAC has been published 151 times since Oct 4, 2023.

FDA first approved this application on Dec 15, 2015.

GNP ANTI-DIARRHEAL 2 MG TABLET

Loperamide Hydrochloride
$0.1335per EA
OTC

Strength

2 mg/1

Manufacturer

AmerisourceBergen

NDC

46122073862

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LOPERAMIDE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA206548

FDA Approved

12/15/2015

On Market Since

7/5/2023

Pharmacological Classes

Opioid Agonist
Opioid Agonists

Price Statistics

The NADAC for GNP ANTI-DIARRHEAL 2 MG TABLET has been published 151 times since Oct 4, 2023, and over the history we have for it it has declined 22.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1335 per EA
All-time high$0.1738 (Feb 14, 2024)
All-time low$0.1233 (Apr 22, 2026)
52-week high$0.1465
52-week low$0.1233
Median price$0.1358
Average price$0.1420
Largest weekly change+22.1% (Jul 17, 2024)
Weeks tracked151
Tracking sinceOct 4, 2023

Price History

1W

-1.9%

1M

-1.9%

3M

+5.5%

6M

+2.3%

1Y

-5.2%

3Y

N/A

5Y

N/A

All

-22.8%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 10% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of GNP ANTI-DIARRHEAL 2 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for GNP ANTI-DIARRHEAL 2 MG TABLET, manufactured by AmerisourceBergen, is $0.1335 per EA (NDC 46122073862), effective Aug 19, 2026.

How has the price of GNP ANTI-DIARRHEAL 2 MG TABLET changed over time?

Over the history we have for it, the NADAC for GNP ANTI-DIARRHEAL 2 MG TABLET has declined 22.8%. It has been tracked across 151 weekly CMS publications since Oct 4, 2023.

What are the highest and lowest recorded NADAC prices for GNP ANTI-DIARRHEAL 2 MG TABLET?

Since Oct 4, 2023, the NADAC for GNP ANTI-DIARRHEAL 2 MG TABLET has ranged from a low of $0.1233 (Apr 22, 2026) to a high of $0.1738 (Feb 14, 2024), with a median of $0.1358 per EA.

Are there cheaper alternatives to GNP ANTI-DIARRHEAL 2 MG TABLET?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, QC ANTI-DIARRHEAL 2 MG CAPLET, is $0.1204 per EA — about 10% below GNP ANTI-DIARRHEAL 2 MG TABLET.

Who manufactures GNP ANTI-DIARRHEAL 2 MG TABLET?

GNP ANTI-DIARRHEAL 2 MG TABLET (NDC 46122073862) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.