Product Information
NAPROXEN 375 MG TABLET is a generic product labeled by Time-Cap Labs Inc., priced at $0.0561 per EA under NDC 49483061701. Its NADAC has been published 503 times since Jan 4, 2017.
FDA first approved this application on Feb 14, 2011. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
375 mg/1
Manufacturer
Time-Cap Labs Inc.NDC
49483061701
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
NAPROXENApproval Type
Generic (ANDA)
FDA Application
ANDA091416FDA Approved
2/14/2011
TE Code
AB
On Market Since
7/6/2016
Pharmacological Classes
Price Statistics
The NADAC for NAPROXEN 375 MG TABLET has been published 503 times since Jan 4, 2017, and over the history we have for it it has declined 3.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0561 per EA |
|---|---|
| All-time high | $0.0808 (Jun 16, 2021) |
| All-time low | $0.0474 (Apr 17, 2024) |
| 52-week high | $0.0607 |
| 52-week low | $0.0561 |
| Median price | $0.0656 |
| Average price | $0.0664 |
| Largest weekly change | -28.8% (Apr 17, 2024) |
| Weeks tracked | 503 |
| Tracking since | Jan 4, 2017 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of NAPROXEN 375 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN 375 MG TABLET, manufactured by Time-Cap Labs Inc., is $0.0561 per EA (NDC 49483061701), effective Aug 19, 2026.
How has the price of NAPROXEN 375 MG TABLET changed over time?
Over the history we have for it, the NADAC for NAPROXEN 375 MG TABLET has declined 3.6%. It has been tracked across 503 weekly CMS publications since Jan 4, 2017.
What are the highest and lowest recorded NADAC prices for NAPROXEN 375 MG TABLET?
Since Jan 4, 2017, the NADAC for NAPROXEN 375 MG TABLET has ranged from a low of $0.0474 (Apr 17, 2024) to a high of $0.0808 (Jun 16, 2021), with a median of $0.0656 per EA.
Are there cheaper alternatives to NAPROXEN 375 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as NAPROXEN 375 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures NAPROXEN 375 MG TABLET?
NAPROXEN 375 MG TABLET (NDC 49483061701) is labeled by Time-Cap Labs Inc., and CMS classifies it as a generic product.