Naproxen
75 NDCs across 18 manufacturers|75 Generic,0 Brand
Naproxen is used to treat juvenile arthritis, rheumatoid arthritis, back pain, bursitis, common cold and dysmenorrhea, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Oct 30, 1992. FDA's Orange Book lists 42 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $36 million on Naproxen across 2.9 million claims for 1.4 million beneficiaries.
Naproxen is available as 75 NDCs from 18 manufacturers (75 generic, 0 brand), with NADAC prices from $0.04 to $3.37 per EA — the most expensive product costs about 77× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
75
75G / 0B
Manufacturers
18
competing in market
Price Spread
$0.04 – $3.37
per EA, 71 of 75 NDCs
7d Activity
avg +0.5% WoW · of 75 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Amneal Pharmaceuticals of New York LLC manufacturer profile
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Lead class
Nonsteroidal Anti-inflammatory Drug class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
18 manufacturers producing NAPROXEN(4 pricing outliers)
Frequently Asked Questions
What is Naproxen used to treat?
Naproxen is used to treat juvenile arthritis, rheumatoid arthritis, back pain, bursitis, common cold and dysmenorrhea, per the National Library of Medicine's MED-RT classification.
When did Naproxen become available as a generic?
FDA approved the first generic Naproxen (ANDA) on Oct 30, 1992. The Orange Book currently lists 42 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Naproxen?
In 2024, Medicare Part D spent $36 million on Naproxen across 2.9 million claims for 1.4 million beneficiaries.
How many Naproxen products are on the market?
The Naproxen drug market contains 75 NDCs from 18 manufacturers — 75 generic and 0 brand products.
What is the price range for Naproxen?
NADAC reference prices for Naproxen range from $0.0436 to $3.3661 per EA — the most expensive product costs about 77× the cheapest. 4 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Which manufacturers make Naproxen?
18 manufacturers list Naproxen in NADAC. Ranked by number of NDCs, the largest are Amneal Pharmaceuticals of New York LLC (9), Amneal Pharmaceuticals LLC (9), Glenmark Pharmaceuticals Inc., USA (8), Cipla USA Inc. (7), Granules Pharmaceuticals Inc. (7).
How has the price of Naproxen changed recently?
Over the past 7 days, 17 Naproxen NDCs rose and 35 fell, with a market-wide average change of +0.5%.