Product Information
METFORMIN ER 1,000 MG OSM-TAB is a generic product labeled by ScieGen Pharmaceuticals, Inc., priced at $0.3142 per EA under NDC 50228050460. Its NADAC has been published 199 times since Dec 14, 2022.
FDA first approved this application on Feb 22, 2022. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1000 mg/1
Manufacturer
ScieGen Pharmaceuticals, Inc.NDC
50228050460
Classification
Generic
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA214629FDA Approved
2/22/2022
TE Code
AB2
On Market Since
2/22/2022
Pharmacological Classes
Price Statistics
The NADAC for METFORMIN ER 1,000 MG OSM-TAB has been published 199 times since Dec 14, 2022, and over the history we have for it it has declined 47.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3142 per EA |
|---|---|
| All-time high | $0.7566 (Mar 13, 2024) |
| All-time low | $0.2243 (Feb 18, 2026) |
| 52-week high | $0.3262 |
| 52-week low | $0.2243 |
| Median price | $0.3413 |
| Average price | $0.3940 |
| Largest weekly change | -49.2% (Apr 17, 2024) |
| Weeks tracked | 199 |
| Tracking since | Dec 14, 2022 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
ScieGen Pharmaceuticals, Inc. manufacturer profile
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Drug market
Metformin Hydrochloride Extended-Release Tablets market comparison
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Therapeutic class
Biguanide class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METFORMIN ER 1,000 MG OSM-TAB?
The current National Average Drug Acquisition Cost (NADAC) for METFORMIN ER 1,000 MG OSM-TAB, manufactured by ScieGen Pharmaceuticals, Inc., is $0.3142 per EA (NDC 50228050460), effective Sep 30, 2026.
How has the price of METFORMIN ER 1,000 MG OSM-TAB changed over time?
Over the history we have for it, the NADAC for METFORMIN ER 1,000 MG OSM-TAB has declined 47.2%. It has been tracked across 199 weekly CMS publications since Dec 14, 2022.
What are the highest and lowest recorded NADAC prices for METFORMIN ER 1,000 MG OSM-TAB?
Since Dec 14, 2022, the NADAC for METFORMIN ER 1,000 MG OSM-TAB has ranged from a low of $0.2243 (Feb 18, 2026) to a high of $0.7566 (Mar 13, 2024), with a median of $0.3413 per EA.
Are there cheaper alternatives to METFORMIN ER 1,000 MG OSM-TAB?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as METFORMIN ER 1,000 MG OSM-TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures METFORMIN ER 1,000 MG OSM-TAB?
METFORMIN ER 1,000 MG OSM-TAB (NDC 50228050460) is labeled by ScieGen Pharmaceuticals, Inc., and CMS classifies it as a generic product.