Product Information
DOXYCYCLINE HYCLATE 100 MG TAB is a generic product labeled by AvPAK, priced at $0.1129 per EA under NDC 50268027915. Its NADAC has been published 458 times since Nov 15, 2017.
FDA first approved this application on Jul 10, 1986. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
AvPAKNDC
50268027915
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
DOXYCYCLINE HYCLATEApproval Type
Generic (ANDA)
FDA Application
ANDA062677FDA Approved
7/10/1986
TE Code
AB
On Market Since
6/4/2014
Pharmacological Classes
Price Statistics
The NADAC for DOXYCYCLINE HYCLATE 100 MG TAB has been published 458 times since Nov 15, 2017, and over the history we have for it it has declined 77.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1129 per EA |
|---|---|
| All-time high | $0.5080 (Nov 15, 2017) |
| All-time low | $0.0950 (Nov 20, 2024) |
| 52-week high | $0.1241 |
| 52-week low | $0.1129 |
| Median price | $0.1411 |
| Average price | $0.1690 |
| Largest weekly change | +40.4% (Aug 21, 2024) |
| Weeks tracked | 458 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DOXYCYCLINE HYCLATE 100 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for DOXYCYCLINE HYCLATE 100 MG TAB, manufactured by AvPAK, is $0.1129 per EA (NDC 50268027915), effective Aug 19, 2026.
How has the price of DOXYCYCLINE HYCLATE 100 MG TAB changed over time?
Over the history we have for it, the NADAC for DOXYCYCLINE HYCLATE 100 MG TAB has declined 77.8%. It has been tracked across 458 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for DOXYCYCLINE HYCLATE 100 MG TAB?
Since Nov 15, 2017, the NADAC for DOXYCYCLINE HYCLATE 100 MG TAB has ranged from a low of $0.0950 (Nov 20, 2024) to a high of $0.5080 (Nov 15, 2017), with a median of $0.1411 per EA.
Are there cheaper alternatives to DOXYCYCLINE HYCLATE 100 MG TAB?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DOXYCYCLINE HYCLATE 100 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures DOXYCYCLINE HYCLATE 100 MG TAB?
DOXYCYCLINE HYCLATE 100 MG TAB (NDC 50268027915) is labeled by AvPAK, and CMS classifies it as a generic product.