Product Information
ENTACAPONE 200 MG TABLET is a generic product labeled by AvPAK, priced at $0.3246 per EA under NDC 50268029515. Its NADAC has been published 464 times since Nov 15, 2017.
FDA first approved this application on Jun 19, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
200 mg/1
Manufacturer
AvPAKNDC
50268029515
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ENTACAPONEApproval Type
Generic (ANDA)
FDA Application
ANDA203437FDA Approved
6/19/2015
TE Code
AB
On Market Since
12/5/2016
Pharmacological Classes
Price Statistics
The NADAC for ENTACAPONE 200 MG TABLET has been published 464 times since Nov 15, 2017, and over the history we have for it it has declined 76.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3246 per EA |
|---|---|
| All-time high | $1.3895 (Nov 15, 2017) |
| All-time low | $0.2327 (Jul 17, 2024) |
| 52-week high | $0.3628 |
| 52-week low | $0.3192 |
| Median price | $0.4294 |
| Average price | $0.5408 |
| Largest weekly change | +59.1% (Aug 21, 2024) |
| Weeks tracked | 464 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AvPAK manufacturer profile
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Drug market
Entacapone market comparison
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Therapeutic class
Catechol-O-Methyltransferase Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ENTACAPONE 200 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ENTACAPONE 200 MG TABLET, manufactured by AvPAK, is $0.3246 per EA (NDC 50268029515), effective Sep 30, 2026.
How has the price of ENTACAPONE 200 MG TABLET changed over time?
Over the history we have for it, the NADAC for ENTACAPONE 200 MG TABLET has declined 76.6%. It has been tracked across 464 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for ENTACAPONE 200 MG TABLET?
Since Nov 15, 2017, the NADAC for ENTACAPONE 200 MG TABLET has ranged from a low of $0.2327 (Jul 17, 2024) to a high of $1.3895 (Nov 15, 2017), with a median of $0.4294 per EA.
Are there cheaper alternatives to ENTACAPONE 200 MG TABLET?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ENTACAPONE 200 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures ENTACAPONE 200 MG TABLET?
ENTACAPONE 200 MG TABLET (NDC 50268029515) is labeled by AvPAK, and CMS classifies it as a generic product.