Product Information

CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.6967 per EA under NDC 16571068901. Its NADAC has been published 131 times since Feb 21, 2024.

FDA first approved this application on Jan 25, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB

CARBIDOPA, LEVODOPA AND ENTACAPONE
$0.6967per EA

Strength

12.5; 200; 50 mg/1; mg/1; mg/1

NDC

16571068901

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

7/22/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA213212

FDA Approved

1/25/2022

TE Code

AB

On Market Since

8/5/2021

Pharmacological Classes

Amino Acids
Aromatic
Aromatic Amino Acid
Catechol O-Methyltransferase Inhibitors
Catechol-O-Methyltransferase Inhibitor

Price Statistics

The NADAC for CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB has been published 131 times since Feb 21, 2024, and over the history we have for it it has declined 26.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.6967 per EA
All-time high$1.1038 (Dec 10, 2025)
All-time low$0.6891 (Apr 22, 2026)
52-week high$1.1038
52-week low$0.6891
Median price$0.8989
Average price$0.8982
Largest weekly change+26.0% (Nov 20, 2024)
Weeks tracked131
Tracking sinceFeb 21, 2024

Price History

1W

0.0%

1M

0.0%

3M

-0.2%

6M

-7.0%

1Y

-32.1%

3Y

N/A

5Y

N/A

All

-26.5%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the CARBIDOPA, LEVODOPA AND ENTACAPONE market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB, manufactured by Rising Pharma Holdings Inc., is $0.6967 per EA (NDC 16571068901), effective Aug 19, 2026.

How has the price of CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB changed over time?

Over the history we have for it, the NADAC for CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB has declined 26.5%. It has been tracked across 131 weekly CMS publications since Feb 21, 2024.

What are the highest and lowest recorded NADAC prices for CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB?

Since Feb 21, 2024, the NADAC for CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB has ranged from a low of $0.6891 (Apr 22, 2026) to a high of $1.1038 (Dec 10, 2025), with a median of $0.8989 per EA.

Are there cheaper alternatives to CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB?

No other NADAC-published product currently shares the active ingredient and strength of CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB?

CARBIDOPA-LEVODOPA-ENTACAPONE 12.5-50-200 MG TAB (NDC 16571068901) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.