Product Information
GUANFACINE 2 MG TABLET is a generic product labeled by AvPAK, priced at $0.2673 per EA under NDC 50268037415. Its NADAC has been published 405 times since Nov 15, 2017.
FDA first approved this application on Nov 25, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2 mg/1
Manufacturer
AvPAKNDC
50268037415
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
GUANFACINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075109FDA Approved
11/25/1998
TE Code
AB
On Market Since
6/7/2017
Pharmacological Classes
Price Statistics
The NADAC for GUANFACINE 2 MG TABLET has been published 405 times since Nov 15, 2017, and over the history we have for it it has risen 158.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2673 per EA |
|---|---|
| All-time high | $0.8375 (Dec 16, 2020) |
| All-time low | $0.0963 (Dec 20, 2017) |
| 52-week high | $0.3037 |
| 52-week low | $0.2410 |
| Median price | $0.4552 |
| Average price | $0.4603 |
| Largest weekly change | +166.3% (Apr 22, 2020) |
| Weeks tracked | 405 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 45% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AvPAK manufacturer profile
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Drug market
Guanfacine market comparison
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Therapeutic class
Central alpha-2 Adrenergic Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GUANFACINE 2 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GUANFACINE 2 MG TABLET, manufactured by AvPAK, is $0.2673 per EA (NDC 50268037415), effective Sep 30, 2026.
How has the price of GUANFACINE 2 MG TABLET changed over time?
Over the history we have for it, the NADAC for GUANFACINE 2 MG TABLET has risen 158.6%. It has been tracked across 405 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for GUANFACINE 2 MG TABLET?
Since Nov 15, 2017, the NADAC for GUANFACINE 2 MG TABLET has ranged from a low of $0.0963 (Dec 20, 2017) to a high of $0.8375 (Dec 16, 2020), with a median of $0.4552 per EA.
Are there cheaper alternatives to GUANFACINE 2 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUANFACINE HCL ER 2 MG TABLET, is $0.1477 per EA — about 45% below GUANFACINE 2 MG TABLET.
Who manufactures GUANFACINE 2 MG TABLET?
GUANFACINE 2 MG TABLET (NDC 50268037415) is labeled by AvPAK, and CMS classifies it as a generic product.