Product Information

GUANFACINE 2 MG TABLET is a generic product labeled by AvPAK, priced at $0.2721 per EA under NDC 50268037415. Its NADAC has been published 399 times since Nov 15, 2017.

FDA first approved this application on Nov 25, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

GUANFACINE 2 MG TABLET

Guanfacine
$0.2721per EA

Strength

2 mg/1

Manufacturer

AvPAK

NDC

50268037415

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

GUANFACINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA075109

FDA Approved

11/25/1998

TE Code

AB

On Market Since

6/7/2017

Pharmacological Classes

Adrenergic alpha2-Agonists
Central alpha-2 Adrenergic Agonist

Price Statistics

The NADAC for GUANFACINE 2 MG TABLET has been published 399 times since Nov 15, 2017, and over the history we have for it it has risen 163.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2721 per EA
All-time high$0.8375 (Dec 16, 2020)
All-time low$0.0963 (Dec 20, 2017)
52-week high$0.3114
52-week low$0.2410
Median price$0.4651
Average price$0.4631
Largest weekly change+166.3% (Apr 22, 2020)
Weeks tracked399
Tracking sinceNov 15, 2017

Price History

1W

+2.8%

1M

+2.8%

3M

+6.2%

6M

+12.9%

1Y

-12.6%

3Y

-57.3%

5Y

-64.5%

All

+163.3%

Generic Alternatives

The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 42% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of GUANFACINE 2 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for GUANFACINE 2 MG TABLET, manufactured by AvPAK, is $0.2721 per EA (NDC 50268037415), effective Aug 19, 2026.

How has the price of GUANFACINE 2 MG TABLET changed over time?

Over the history we have for it, the NADAC for GUANFACINE 2 MG TABLET has risen 163.3%. It has been tracked across 399 weekly CMS publications since Nov 15, 2017.

What are the highest and lowest recorded NADAC prices for GUANFACINE 2 MG TABLET?

Since Nov 15, 2017, the NADAC for GUANFACINE 2 MG TABLET has ranged from a low of $0.0963 (Dec 20, 2017) to a high of $0.8375 (Dec 16, 2020), with a median of $0.4651 per EA.

Are there cheaper alternatives to GUANFACINE 2 MG TABLET?

Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUANFACINE HCL ER 2 MG TABLET, is $0.1573 per EA — about 42% below GUANFACINE 2 MG TABLET.

Who manufactures GUANFACINE 2 MG TABLET?

GUANFACINE 2 MG TABLET (NDC 50268037415) is labeled by AvPAK, and CMS classifies it as a generic product.