Product Information
GUANFACINE HCL ER 2 MG TABLET is a generic product labeled by NorthStar Rx LLC, priced at $0.2079 per EA under NDC 16714019101. Its NADAC has been published 179 times since Jun 1, 2022.
FDA first approved this application on Nov 16, 2017.
Strength
2 mg/1
Manufacturer
NorthStar Rx LLCNDC
16714019101
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
10/22/2025
Active Ingredients
GUANFACINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA205689FDA Approved
11/16/2017
On Market Since
9/17/2021
Pharmacological Classes
Price Statistics
The NADAC for GUANFACINE HCL ER 2 MG TABLET has been published 179 times since Jun 1, 2022, and over the history we have for it it has declined 20.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2079 per EA |
|---|---|
| All-time high | $0.2769 (Aug 10, 2022) |
| All-time low | $0.1705 (Nov 20, 2024) |
| 52-week high | $0.2079 |
| 52-week low | $0.1978 |
| Median price | $0.2172 |
| Average price | $0.2178 |
| Largest weekly change | +25.8% (Jun 19, 2024) |
| Weeks tracked | 179 |
| Tracking since | Jun 1, 2022 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
+5.1%
3Y
-9.8%
5Y
N/A
All
-20.8%
Last surveyed Oct 29, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 29% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
NorthStar Rx LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Guanfacine market comparison
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Therapeutic class
Central alpha-2 Adrenergic Agonist class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GUANFACINE HCL ER 2 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GUANFACINE HCL ER 2 MG TABLET, manufactured by NorthStar Rx LLC, is $0.2079 per EA (NDC 16714019101), effective Oct 29, 2025.
How has the price of GUANFACINE HCL ER 2 MG TABLET changed over time?
Over the history we have for it, the NADAC for GUANFACINE HCL ER 2 MG TABLET has declined 20.8%. It has been tracked across 179 weekly CMS publications since Jun 1, 2022.
What are the highest and lowest recorded NADAC prices for GUANFACINE HCL ER 2 MG TABLET?
Since Jun 1, 2022, the NADAC for GUANFACINE HCL ER 2 MG TABLET has ranged from a low of $0.1705 (Nov 20, 2024) to a high of $0.2769 (Aug 10, 2022), with a median of $0.2172 per EA.
Are there cheaper alternatives to GUANFACINE HCL ER 2 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUANFACINE HCL ER 2 MG TABLET, is $0.1477 per EA — about 29% below GUANFACINE HCL ER 2 MG TABLET.
Who manufactures GUANFACINE HCL ER 2 MG TABLET?
GUANFACINE HCL ER 2 MG TABLET (NDC 16714019101) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.