Product Information
GUANFACINE 2 MG TABLET is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $0.2673 per EA under NDC 53746071301. Its NADAC has been published 221 times since Jul 13, 2022.
FDA first approved this application on Nov 25, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2 mg/1
Manufacturer
Amneal Pharmaceuticals of New York LLCNDC
53746071301
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
GUANFACINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075109FDA Approved
11/25/1998
TE Code
AB
On Market Since
4/15/2022
Pharmacological Classes
Price Statistics
The NADAC for GUANFACINE 2 MG TABLET has been published 221 times since Jul 13, 2022, and over the history we have for it it has declined 63.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2673 per EA |
|---|---|
| All-time high | $0.7339 (Jul 13, 2022) |
| All-time low | $0.2410 (Feb 18, 2026) |
| 52-week high | $0.3037 |
| 52-week low | $0.2410 |
| Median price | $0.3448 |
| Average price | $0.4326 |
| Largest weekly change | +61.2% (Aug 21, 2024) |
| Weeks tracked | 221 |
| Tracking since | Jul 13, 2022 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 45% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Amneal Pharmaceuticals of New York LLC manufacturer profile
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Drug market
Guanfacine market comparison
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Therapeutic class
Central alpha-2 Adrenergic Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GUANFACINE 2 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GUANFACINE 2 MG TABLET, manufactured by Amneal Pharmaceuticals of New York LLC, is $0.2673 per EA (NDC 53746071301), effective Sep 30, 2026.
How has the price of GUANFACINE 2 MG TABLET changed over time?
Over the history we have for it, the NADAC for GUANFACINE 2 MG TABLET has declined 63.6%. It has been tracked across 221 weekly CMS publications since Jul 13, 2022.
What are the highest and lowest recorded NADAC prices for GUANFACINE 2 MG TABLET?
Since Jul 13, 2022, the NADAC for GUANFACINE 2 MG TABLET has ranged from a low of $0.2410 (Feb 18, 2026) to a high of $0.7339 (Jul 13, 2022), with a median of $0.3448 per EA.
Are there cheaper alternatives to GUANFACINE 2 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUANFACINE HCL ER 2 MG TABLET, is $0.1477 per EA — about 45% below GUANFACINE 2 MG TABLET.
Who manufactures GUANFACINE 2 MG TABLET?
GUANFACINE 2 MG TABLET (NDC 53746071301) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.