Product Information
GUANFACINE 2 MG TABLET is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $0.2721 per EA under NDC 53746071301. Its NADAC has been published 215 times since Jul 13, 2022.
FDA first approved this application on Nov 25, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2 mg/1
Manufacturer
Amneal Pharmaceuticals of New York LLCNDC
53746071301
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
GUANFACINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075109FDA Approved
11/25/1998
TE Code
AB
On Market Since
4/15/2022
Pharmacological Classes
Price Statistics
The NADAC for GUANFACINE 2 MG TABLET has been published 215 times since Jul 13, 2022, and over the history we have for it it has declined 62.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2721 per EA |
|---|---|
| All-time high | $0.7339 (Jul 13, 2022) |
| All-time low | $0.2410 (Feb 18, 2026) |
| 52-week high | $0.3114 |
| 52-week low | $0.2410 |
| Median price | $0.4117 |
| Average price | $0.4371 |
| Largest weekly change | +61.2% (Aug 21, 2024) |
| Weeks tracked | 215 |
| Tracking since | Jul 13, 2022 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 42% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of GUANFACINE 2 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GUANFACINE 2 MG TABLET, manufactured by Amneal Pharmaceuticals of New York LLC, is $0.2721 per EA (NDC 53746071301), effective Aug 19, 2026.
How has the price of GUANFACINE 2 MG TABLET changed over time?
Over the history we have for it, the NADAC for GUANFACINE 2 MG TABLET has declined 62.9%. It has been tracked across 215 weekly CMS publications since Jul 13, 2022.
What are the highest and lowest recorded NADAC prices for GUANFACINE 2 MG TABLET?
Since Jul 13, 2022, the NADAC for GUANFACINE 2 MG TABLET has ranged from a low of $0.2410 (Feb 18, 2026) to a high of $0.7339 (Jul 13, 2022), with a median of $0.4117 per EA.
Are there cheaper alternatives to GUANFACINE 2 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUANFACINE HCL ER 2 MG TABLET, is $0.1573 per EA — about 42% below GUANFACINE 2 MG TABLET.
Who manufactures GUANFACINE 2 MG TABLET?
GUANFACINE 2 MG TABLET (NDC 53746071301) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.