Product Information
LOPERAMIDE 2 MG CAPSULE is a generic product labeled by AvPAK, priced at $0.0565 per EA under NDC 50268048215. Its NADAC has been published 150 times since Oct 11, 2023.
FDA first approved this application on Oct 22, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2 mg/1
Manufacturer
AvPAKNDC
50268048215
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
LOPERAMIDE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA215579FDA Approved
10/22/2021
TE Code
AB
On Market Since
4/5/2023
Pharmacological Classes
Price Statistics
The NADAC for LOPERAMIDE 2 MG CAPSULE has been published 150 times since Oct 11, 2023, and over the history we have for it it has declined 77.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0565 per EA |
|---|---|
| All-time high | $0.2541 (Dec 13, 2023) |
| All-time low | $0.0520 (Feb 18, 2026) |
| 52-week high | $0.1007 |
| 52-week low | $0.0520 |
| Median price | $0.1253 |
| Average price | $0.1313 |
| Largest weekly change | +44.3% (Aug 21, 2024) |
| Weeks tracked | 150 |
| Tracking since | Oct 11, 2023 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LOPERAMIDE 2 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for LOPERAMIDE 2 MG CAPSULE, manufactured by AvPAK, is $0.0565 per EA (NDC 50268048215), effective Aug 19, 2026.
How has the price of LOPERAMIDE 2 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for LOPERAMIDE 2 MG CAPSULE has declined 77.5%. It has been tracked across 150 weekly CMS publications since Oct 11, 2023.
What are the highest and lowest recorded NADAC prices for LOPERAMIDE 2 MG CAPSULE?
Since Oct 11, 2023, the NADAC for LOPERAMIDE 2 MG CAPSULE has ranged from a low of $0.0520 (Feb 18, 2026) to a high of $0.2541 (Dec 13, 2023), with a median of $0.1253 per EA.
Are there cheaper alternatives to LOPERAMIDE 2 MG CAPSULE?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LOPERAMIDE 2 MG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures LOPERAMIDE 2 MG CAPSULE?
LOPERAMIDE 2 MG CAPSULE (NDC 50268048215) is labeled by AvPAK, and CMS classifies it as a generic product.