Product Information
MIDODRINE HCL 2.5 MG TABLET is a generic product labeled by AvPAK, priced at $0.0728 per EA under NDC 50268056115. Its NADAC has been published 352 times since Nov 27, 2019.
FDA first approved this application on Sep 12, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5 mg/1
Manufacturer
AvPAKNDC
50268056115
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
MIDODRINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA077746FDA Approved
9/12/2006
TE Code
AB
On Market Since
8/26/2019
Pharmacological Classes
Price Statistics
The NADAC for MIDODRINE HCL 2.5 MG TABLET has been published 352 times since Nov 27, 2019, and over the history we have for it it has declined 78.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0728 per EA |
|---|---|
| All-time high | $0.4071 (Apr 15, 2020) |
| All-time low | $0.0668 (Nov 20, 2024) |
| 52-week high | $0.0740 |
| 52-week low | $0.0703 |
| Median price | $0.1769 |
| Average price | $0.1711 |
| Largest weekly change | +59.2% (Nov 22, 2023) |
| Weeks tracked | 352 |
| Tracking since | Nov 27, 2019 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MIDODRINE HCL 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for MIDODRINE HCL 2.5 MG TABLET, manufactured by AvPAK, is $0.0728 per EA (NDC 50268056115), effective Aug 19, 2026.
How has the price of MIDODRINE HCL 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for MIDODRINE HCL 2.5 MG TABLET has declined 78.4%. It has been tracked across 352 weekly CMS publications since Nov 27, 2019.
What are the highest and lowest recorded NADAC prices for MIDODRINE HCL 2.5 MG TABLET?
Since Nov 27, 2019, the NADAC for MIDODRINE HCL 2.5 MG TABLET has ranged from a low of $0.0668 (Nov 20, 2024) to a high of $0.4071 (Apr 15, 2020), with a median of $0.1769 per EA.
Are there cheaper alternatives to MIDODRINE HCL 2.5 MG TABLET?
11 manufacturers publish a NADAC-priced product with the same active ingredient and strength as MIDODRINE HCL 2.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures MIDODRINE HCL 2.5 MG TABLET?
MIDODRINE HCL 2.5 MG TABLET (NDC 50268056115) is labeled by AvPAK, and CMS classifies it as a generic product.