Product Information
MIDODRINE HCL 2.5 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0737 per EA under NDC 00904681706. Its NADAC has been published 258 times since Oct 27, 2021.
FDA first approved this application on Sep 12, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The Low Outlier badge above means this manufacturer's average price in the Midodrine Hydrochloride market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
2.5 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904681706
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
MIDODRINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA077746FDA Approved
9/12/2006
TE Code
AB
On Market Since
9/12/2006
Pharmacological Classes
Price Statistics
The NADAC for MIDODRINE HCL 2.5 MG TABLET has been published 258 times since Oct 27, 2021, and over the history we have for it it has declined 68.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0737 per EA |
|---|---|
| All-time high | $0.2450 (Dec 15, 2021) |
| All-time low | $0.0668 (Nov 20, 2024) |
| 52-week high | $0.0740 |
| 52-week low | $0.0703 |
| Median price | $0.1105 |
| Average price | $0.1297 |
| Largest weekly change | +59.2% (Nov 22, 2023) |
| Weeks tracked | 258 |
| Tracking since | Oct 27, 2021 |
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Major Pharmaceuticals manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Midodrine Hydrochloride market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
alpha-Adrenergic Agonist class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of MIDODRINE HCL 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for MIDODRINE HCL 2.5 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0737 per EA (NDC 00904681706), effective Sep 30, 2026.
How has the price of MIDODRINE HCL 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for MIDODRINE HCL 2.5 MG TABLET has declined 68.5%. It has been tracked across 258 weekly CMS publications since Oct 27, 2021.
What are the highest and lowest recorded NADAC prices for MIDODRINE HCL 2.5 MG TABLET?
Since Oct 27, 2021, the NADAC for MIDODRINE HCL 2.5 MG TABLET has ranged from a low of $0.0668 (Nov 20, 2024) to a high of $0.2450 (Dec 15, 2021), with a median of $0.1105 per EA.
Are there cheaper alternatives to MIDODRINE HCL 2.5 MG TABLET?
12 manufacturers publish a NADAC-priced product with the same active ingredient and strength as MIDODRINE HCL 2.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures MIDODRINE HCL 2.5 MG TABLET?
MIDODRINE HCL 2.5 MG TABLET (NDC 00904681706) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.