Product Information
SULFAMETHOXAZOLE-TMP SS TABLET is a generic product labeled by AvPAK, priced at $0.0395 per EA under NDC 50268072815. Its NADAC has been published 464 times since Nov 15, 2017.
FDA first approved this application on Feb 16, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
400; 80 mg/1; mg/1
Manufacturer
AvPAKNDC
50268072815
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
SULFAMETHOXAZOLE; TRIMETHOPRIMApproval Type
Generic (ANDA)
FDA Application
ANDA090624FDA Approved
2/16/2010
TE Code
AB
On Market Since
9/23/2014
Pharmacological Classes
Price Statistics
The NADAC for SULFAMETHOXAZOLE-TMP SS TABLET has been published 464 times since Nov 15, 2017, and over the history we have for it it has declined 60.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0395 per EA |
|---|---|
| All-time high | $0.1018 (Mar 14, 2018) |
| All-time low | $0.0378 (Nov 19, 2025) |
| 52-week high | $0.0410 |
| 52-week low | $0.0378 |
| Median price | $0.0638 |
| Average price | $0.0635 |
| Largest weekly change | +39.0% (Mar 20, 2024) |
| Weeks tracked | 464 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AvPAK manufacturer profile
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Drug market
Sulfamethoxazole and Trimethoprim market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Dihydrofolate Reductase Inhibitor Antibacterial class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of SULFAMETHOXAZOLE-TMP SS TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SULFAMETHOXAZOLE-TMP SS TABLET, manufactured by AvPAK, is $0.0395 per EA (NDC 50268072815), effective Sep 30, 2026.
How has the price of SULFAMETHOXAZOLE-TMP SS TABLET changed over time?
Over the history we have for it, the NADAC for SULFAMETHOXAZOLE-TMP SS TABLET has declined 60.5%. It has been tracked across 464 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for SULFAMETHOXAZOLE-TMP SS TABLET?
Since Nov 15, 2017, the NADAC for SULFAMETHOXAZOLE-TMP SS TABLET has ranged from a low of $0.0378 (Nov 19, 2025) to a high of $0.1018 (Mar 14, 2018), with a median of $0.0638 per EA.
Are there cheaper alternatives to SULFAMETHOXAZOLE-TMP SS TABLET?
Yes. 8 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SULFAMETHOXAZOLE-TMP SS TABLET, is $0.0385 per EA — about 2% below SULFAMETHOXAZOLE-TMP SS TABLET.
Who manufactures SULFAMETHOXAZOLE-TMP SS TABLET?
SULFAMETHOXAZOLE-TMP SS TABLET (NDC 50268072815) is labeled by AvPAK, and CMS classifies it as a generic product.