Product Information
SULFAMETHOXAZOLE-TMP SS TABLET is a generic product labeled by AvPAK, priced at $0.0397 per EA under NDC 50268072815. Its NADAC has been published 458 times since Nov 15, 2017.
FDA first approved this application on Feb 16, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
400; 80 mg/1; mg/1
Manufacturer
AvPAKNDC
50268072815
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
SULFAMETHOXAZOLE; TRIMETHOPRIMApproval Type
Generic (ANDA)
FDA Application
ANDA090624FDA Approved
2/16/2010
TE Code
AB
On Market Since
9/23/2014
Pharmacological Classes
Price Statistics
The NADAC for SULFAMETHOXAZOLE-TMP SS TABLET has been published 458 times since Nov 15, 2017, and over the history we have for it it has declined 60.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0397 per EA |
|---|---|
| All-time high | $0.1018 (Mar 14, 2018) |
| All-time low | $0.0378 (Nov 19, 2025) |
| 52-week high | $0.0434 |
| 52-week low | $0.0378 |
| Median price | $0.0641 |
| Average price | $0.0638 |
| Largest weekly change | +39.0% (Mar 20, 2024) |
| Weeks tracked | 458 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SULFAMETHOXAZOLE-TMP SS TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SULFAMETHOXAZOLE-TMP SS TABLET, manufactured by AvPAK, is $0.0397 per EA (NDC 50268072815), effective Aug 19, 2026.
How has the price of SULFAMETHOXAZOLE-TMP SS TABLET changed over time?
Over the history we have for it, the NADAC for SULFAMETHOXAZOLE-TMP SS TABLET has declined 60.2%. It has been tracked across 458 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for SULFAMETHOXAZOLE-TMP SS TABLET?
Since Nov 15, 2017, the NADAC for SULFAMETHOXAZOLE-TMP SS TABLET has ranged from a low of $0.0378 (Nov 19, 2025) to a high of $0.1018 (Mar 14, 2018), with a median of $0.0641 per EA.
Are there cheaper alternatives to SULFAMETHOXAZOLE-TMP SS TABLET?
Yes. 8 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SULFAMETHOXAZOLE-TMP SS TABLET, is $0.0385 per EA — about 3% below SULFAMETHOXAZOLE-TMP SS TABLET.
Who manufactures SULFAMETHOXAZOLE-TMP SS TABLET?
SULFAMETHOXAZOLE-TMP SS TABLET (NDC 50268072815) is labeled by AvPAK, and CMS classifies it as a generic product.