Product Information

SULFAMETHOXAZOLE-TMP SS TABLET is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $0.0397 per EA under NDC 53746027105. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Jan 27, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

SULFAMETHOXAZOLE-TMP SS TABLET

Sulfamethoxazole and Trimethoprim
$0.0397per EA

Strength

400; 80 mg/1; mg/1

NDC

53746027105

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA076899

FDA Approved

1/27/2005

TE Code

AB

On Market Since

2/25/2010

Pharmacological Classes

Cytochrome P450 2C8 Inhibitors
Cytochrome P450 2C9 Inhibitors
Dihydrofolate Reductase Inhibitor Antibacterial
Dihydrofolate Reductase Inhibitors
Organic Cation Transporter 2 Inhibitors
Sulfonamide Antimicrobial
Sulfonamides

Price Statistics

The NADAC for SULFAMETHOXAZOLE-TMP SS TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 50.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0397 per EA
All-time high$0.1231 (Jan 11, 2017)
All-time low$0.0378 (Nov 19, 2025)
52-week high$0.0434
52-week low$0.0378
Median price$0.0732
Average price$0.0750
Largest weekly change+39.0% (Mar 20, 2024)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+2.6%

1M

+2.6%

3M

+0.5%

6M

+1.3%

1Y

-8.5%

3Y

-12.9%

5Y

-39.3%

All

-50.8%

Generic Alternatives

The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SULFAMETHOXAZOLE-TMP SS TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SULFAMETHOXAZOLE-TMP SS TABLET, manufactured by Amneal Pharmaceuticals of New York LLC, is $0.0397 per EA (NDC 53746027105), effective Aug 19, 2026.

How has the price of SULFAMETHOXAZOLE-TMP SS TABLET changed over time?

Over the history we have for it, the NADAC for SULFAMETHOXAZOLE-TMP SS TABLET has declined 50.8%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for SULFAMETHOXAZOLE-TMP SS TABLET?

Since Nov 28, 2013, the NADAC for SULFAMETHOXAZOLE-TMP SS TABLET has ranged from a low of $0.0378 (Nov 19, 2025) to a high of $0.1231 (Jan 11, 2017), with a median of $0.0732 per EA.

Are there cheaper alternatives to SULFAMETHOXAZOLE-TMP SS TABLET?

Yes. 9 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SULFAMETHOXAZOLE-TMP SS TABLET, is $0.0385 per EA — about 3% below SULFAMETHOXAZOLE-TMP SS TABLET.

Who manufactures SULFAMETHOXAZOLE-TMP SS TABLET?

SULFAMETHOXAZOLE-TMP SS TABLET (NDC 53746027105) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.