Strength
325; 37.5 mg/1; mg/1
Manufacturer
AvPAKNDC
50268077415
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
ACETAMINOPHEN; TRAMADOL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA090485On Market Since
1/14/2015
Pharmacological Classes
Price Statistics
The NADAC for TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB has been published 450 times since Nov 15, 2017, and over the history we have for it it has declined 36.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1054 per EA |
|---|---|
| All-time high | $0.1758 (Sep 12, 2018) |
| All-time low | $0.0806 (Nov 20, 2024) |
| 52-week high | $0.1145 |
| 52-week low | $0.1014 |
| Median price | $0.1182 |
| Average price | $0.1229 |
| Largest weekly change | +26.7% (Aug 21, 2024) |
| Weeks tracked | 450 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB, manufactured by AvPAK, is $0.1054 per EA (NDC 50268077415), effective Jun 24, 2026.
How has the price of TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB changed over time?
Over the history we have for it, the NADAC for TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB has declined 36.0%. It has been tracked across 450 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB?
Since Nov 15, 2017, the NADAC for TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB has ranged from a low of $0.0806 (Nov 20, 2024) to a high of $0.1758 (Sep 12, 2018), with a median of $0.1182 per EA.
Are there cheaper alternatives to TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB?
2 NADAC-published products share the same active ingredient, strength, and dosage form as TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB, but none are currently priced below it.
Who manufactures TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB?
TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB (NDC 50268077415) is labeled by AvPAK, and CMS classifies it as a generic product.
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