Product Information
SPRAVATO 56 MG DOSE PACK is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $426.2990 per EA under NDC 50458002802. Its NADAC has been published 110 times since Jul 17, 2024.
FDA first approved this application on Mar 5, 2019.
Strength
28 mg/.2mL
Manufacturer
Janssen Pharmaceuticals Inc.NDC
50458002802
Classification
Brand
Dosage Form
SOLUTION
Route
NASAL
Effective Date
1/29/2026
Active Ingredients
ESKETAMINE HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA211243FDA Approved
3/5/2019
On Market Since
3/5/2019
Price Statistics
The NADAC for SPRAVATO 56 MG DOSE PACK has been published 110 times since Jul 17, 2024, and over the history we have for it it has risen 13.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $426.2990 per EA |
|---|---|
| All-time high | $426.2990 (Aug 19, 2026) |
| All-time low | $373.2786 (Aug 21, 2024) |
| 52-week high | $426.2990 |
| 52-week low | $395.3764 |
| Median price | $397.2964 |
| Average price | $399.8540 |
| Largest weekly change | +8.0% (Feb 5, 2025) |
| Weeks tracked | 110 |
| Tracking since | Jul 17, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SPRAVATO 56 MG DOSE PACK?
The current National Average Drug Acquisition Cost (NADAC) for SPRAVATO 56 MG DOSE PACK, manufactured by Janssen Pharmaceuticals Inc., is $426.2990 per EA (NDC 50458002802), effective Aug 19, 2026.
How has the price of SPRAVATO 56 MG DOSE PACK changed over time?
Over the history we have for it, the NADAC for SPRAVATO 56 MG DOSE PACK has risen 13.5%. It has been tracked across 110 weekly CMS publications since Jul 17, 2024.
What are the highest and lowest recorded NADAC prices for SPRAVATO 56 MG DOSE PACK?
Since Jul 17, 2024, the NADAC for SPRAVATO 56 MG DOSE PACK has ranged from a low of $373.2786 (Aug 21, 2024) to a high of $426.2990 (Aug 19, 2026), with a median of $397.2964 per EA.
Are there cheaper alternatives to SPRAVATO 56 MG DOSE PACK?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as SPRAVATO 56 MG DOSE PACK in a comparable dosage form, but none are currently priced below it.
Who manufactures SPRAVATO 56 MG DOSE PACK?
SPRAVATO 56 MG DOSE PACK (NDC 50458002802) is labeled by Janssen Pharmaceuticals Inc., and CMS classifies it as a brand product.