Product Information

INVOKAMET 50-500 MG TABLET is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $9.5602 per EA under NDC 50458054060. Its NADAC has been published 467 times since Apr 22, 2015.

INVOKAMET 50-500 MG TABLET

canagliflozin and metformin hydrochloride

$9.5602per EA

Strength

50; 500 mg/1; mg/1

Manufacturer

Janssen Pharmaceuticals Inc.

NDC

50458054060

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

CANAGLIFLOZIN; METFORMIN HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA204353

On Market Since

8/8/2014

Pharmacological Classes

Biguanide

Biguanides

P-Glycoprotein Inhibitors

Sodium-Glucose Cotransporter 2 Inhibitor

Sodium-Glucose Transporter 2 Inhibitors

Price Statistics

The NADAC for INVOKAMET 50-500 MG TABLET has been published 467 times since Apr 22, 2015, and over the history we have for it it has risen 73.8%. The table below summarizes its recorded NADAC range and movement.

Current price	$9.5602 per EA
All-time high	$9.6036 (Sep 11, 2024)
All-time low	$5.5012 (Apr 22, 2015)
52-week high	$9.5709
52-week low	$9.5232
Median price	$7.9092
Average price	$7.8863
Largest weekly change	+10.3% (Apr 17, 2024)
Weeks tracked	467
Tracking since	Apr 22, 2015

Price History

0.0%

+0.1%

+0.0%

+0.2%

+10.1%

All

+73.8%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

INVOKAMET XR 50-500 MG TABLET

Brand

50458094001•Janssen Pharmaceuticals Inc.

$9.6775

+1% more

Frequently asked questions

What is the NADAC price of INVOKAMET 50-500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for INVOKAMET 50-500 MG TABLET, manufactured by Janssen Pharmaceuticals Inc., is $9.5602 per EA (NDC 50458054060), effective Jun 24, 2026.

How has the price of INVOKAMET 50-500 MG TABLET changed over time?

Over the history we have for it, the NADAC for INVOKAMET 50-500 MG TABLET has risen 73.8%. It has been tracked across 467 weekly CMS publications since Apr 22, 2015.

What are the highest and lowest recorded NADAC prices for INVOKAMET 50-500 MG TABLET?

Since Apr 22, 2015, the NADAC for INVOKAMET 50-500 MG TABLET has ranged from a low of $5.5012 (Apr 22, 2015) to a high of $9.6036 (Sep 11, 2024), with a median of $7.9092 per EA.

Are there cheaper alternatives to INVOKAMET 50-500 MG TABLET?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as INVOKAMET 50-500 MG TABLET, but none are currently priced below it.