Product Information

INVOKAMET XR 50-500 MG TABLET is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $9.6775 per EA under NDC 50458094001. Its NADAC has been published 333 times since Oct 18, 2017.

INVOKAMET XR 50-500 MG TABLET

canagliflozin and metformin hydrochloride
$9.6775per EA

Strength

50; 500 mg/1; mg/1

NDC

50458094001

Classification

Brand

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Last Updated

12/17/2025

Approval Type

New Drug (NDA)

FDA Application

NDA205879

On Market Since

9/20/2016

Pharmacological Classes

Biguanide
Biguanides
P-Glycoprotein Inhibitors
Sodium-Glucose Cotransporter 2 Inhibitor
Sodium-Glucose Transporter 2 Inhibitors

Price Statistics

The NADAC for INVOKAMET XR 50-500 MG TABLET has been published 333 times since Oct 18, 2017, and over the history we have for it it has risen 41.5%. The table below summarizes its recorded NADAC range and movement.

Current price$9.6775 per EA
All-time high$9.6775 (Jun 24, 2026)
All-time low$6.8403 (Oct 18, 2017)
52-week high$9.6775
52-week low$9.6486
Median price$8.3043
Average price$8.5729
Largest weekly change+9.8% (Apr 17, 2024)
Weeks tracked333
Tracking sinceOct 18, 2017

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

+0.3%

3Y

+11.2%

5Y

+11.2%

All

+41.5%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 1%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of INVOKAMET XR 50-500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for INVOKAMET XR 50-500 MG TABLET, manufactured by Janssen Pharmaceuticals Inc., is $9.6775 per EA (NDC 50458094001), effective Jun 24, 2026.

How has the price of INVOKAMET XR 50-500 MG TABLET changed over time?

Over the history we have for it, the NADAC for INVOKAMET XR 50-500 MG TABLET has risen 41.5%. It has been tracked across 333 weekly CMS publications since Oct 18, 2017.

What are the highest and lowest recorded NADAC prices for INVOKAMET XR 50-500 MG TABLET?

Since Oct 18, 2017, the NADAC for INVOKAMET XR 50-500 MG TABLET has ranged from a low of $6.8403 (Oct 18, 2017) to a high of $9.6775 (Jun 24, 2026), with a median of $8.3043 per EA.

Are there cheaper alternatives to INVOKAMET XR 50-500 MG TABLET?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, INVOKAMET 50-500 MG TABLET, is $9.5602 per EA — about 1% below INVOKAMET XR 50-500 MG TABLET.

Who manufactures INVOKAMET XR 50-500 MG TABLET?

INVOKAMET XR 50-500 MG TABLET (NDC 50458094001) is labeled by Janssen Pharmaceuticals Inc., and CMS classifies it as a brand product.