Product Information
INVOKAMET XR 50-500 MG TABLET is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $9.6775 per EA under NDC 50458094001. Its NADAC has been published 341 times since Oct 18, 2017.
FDA first approved this application on Sep 20, 2016.
Strength
50; 500 mg/1; mg/1
Manufacturer
Janssen Pharmaceuticals Inc.NDC
50458094001
Classification
Brand
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
12/17/2025
Active Ingredients
CANAGLIFLOZIN; METFORMIN HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA205879FDA Approved
9/20/2016
On Market Since
9/20/2016
Pharmacological Classes
Price Statistics
The NADAC for INVOKAMET XR 50-500 MG TABLET has been published 341 times since Oct 18, 2017, and over the history we have for it it has risen 41.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.6775 per EA |
|---|---|
| All-time high | $9.6775 (Aug 19, 2026) |
| All-time low | $6.8403 (Oct 18, 2017) |
| 52-week high | $9.6775 |
| 52-week low | $9.6652 |
| Median price | $8.7029 |
| Average price | $8.5988 |
| Largest weekly change | +9.8% (Apr 17, 2024) |
| Weeks tracked | 341 |
| Tracking since | Oct 18, 2017 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of INVOKAMET XR 50-500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for INVOKAMET XR 50-500 MG TABLET, manufactured by Janssen Pharmaceuticals Inc., is $9.6775 per EA (NDC 50458094001), effective Aug 19, 2026.
How has the price of INVOKAMET XR 50-500 MG TABLET changed over time?
Over the history we have for it, the NADAC for INVOKAMET XR 50-500 MG TABLET has risen 41.5%. It has been tracked across 341 weekly CMS publications since Oct 18, 2017.
What are the highest and lowest recorded NADAC prices for INVOKAMET XR 50-500 MG TABLET?
Since Oct 18, 2017, the NADAC for INVOKAMET XR 50-500 MG TABLET has ranged from a low of $6.8403 (Oct 18, 2017) to a high of $9.6775 (Aug 19, 2026), with a median of $8.7029 per EA.
Are there cheaper alternatives to INVOKAMET XR 50-500 MG TABLET?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, INVOKAMET 50-500 MG TABLET, is $9.5684 per EA — about 1% below INVOKAMET XR 50-500 MG TABLET.
Who manufactures INVOKAMET XR 50-500 MG TABLET?
INVOKAMET XR 50-500 MG TABLET (NDC 50458094001) is labeled by Janssen Pharmaceuticals Inc., and CMS classifies it as a brand product.