Product Information

INVOKAMET 50-1,000 MG TABLET is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $9.5401 per EA under NDC 50458054160. Its NADAC has been published 606 times since Nov 19, 2014.

INVOKAMET 50-1,000 MG TABLET

canagliflozin and metformin hydrochloride

$9.5401per EA

Strength

50; 1000 mg/1; mg/1

Manufacturer

Janssen Pharmaceuticals Inc.

NDC

50458054160

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

CANAGLIFLOZIN; METFORMIN HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA204353

On Market Since

8/8/2014

Pharmacological Classes

Biguanide

Biguanides

P-Glycoprotein Inhibitors

Sodium-Glucose Cotransporter 2 Inhibitor

Sodium-Glucose Transporter 2 Inhibitors

Price Statistics

The NADAC for INVOKAMET 50-1,000 MG TABLET has been published 606 times since Nov 19, 2014, and over the history we have for it it has risen 92.7%. The table below summarizes its recorded NADAC range and movement.

Current price	$9.5401 per EA
All-time high	$9.5848 (Mar 12, 2025)
All-time low	$4.9190 (Dec 17, 2014)
52-week high	$9.5699
52-week low	$9.5371
Median price	$8.2651
Average price	$8.0777
Largest weekly change	+9.9% (Feb 11, 2015)
Weeks tracked	606
Tracking since	Nov 19, 2014

Price History

0.0%

-0.1%

+0.0%

-0.1%

-0.2%

-0.3%

+9.6%

All

+92.7%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

INVOKAMET XR 50-1,000 MG TAB

Brand

50458094101•Janssen Pharmaceuticals Inc.

$9.6577

+1% more

Frequently asked questions

What is the NADAC price of INVOKAMET 50-1,000 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for INVOKAMET 50-1,000 MG TABLET, manufactured by Janssen Pharmaceuticals Inc., is $9.5401 per EA (NDC 50458054160), effective Jun 24, 2026.

How has the price of INVOKAMET 50-1,000 MG TABLET changed over time?

Over the history we have for it, the NADAC for INVOKAMET 50-1,000 MG TABLET has risen 92.7%. It has been tracked across 606 weekly CMS publications since Nov 19, 2014.

What are the highest and lowest recorded NADAC prices for INVOKAMET 50-1,000 MG TABLET?

Since Nov 19, 2014, the NADAC for INVOKAMET 50-1,000 MG TABLET has ranged from a low of $4.9190 (Dec 17, 2014) to a high of $9.5848 (Mar 12, 2025), with a median of $8.2651 per EA.

Are there cheaper alternatives to INVOKAMET 50-1,000 MG TABLET?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as INVOKAMET 50-1,000 MG TABLET, but none are currently priced below it.