Product Information

INVOKAMET XR 50-1,000 MG TAB is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $9.6876 per EA under NDC 50458094101. Its NADAC has been published 475 times since Jul 19, 2017.

FDA first approved this application on Sep 20, 2016.

INVOKAMET XR 50-1,000 MG TAB

canagliflozin and metformin hydrochloride
$9.6876per EA

Strength

50; 1000 mg/1; mg/1

NDC

50458094101

Classification

Brand

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Approval Type

New Drug (NDA)

FDA Application

NDA205879

FDA Approved

9/20/2016

On Market Since

9/20/2016

Pharmacological Classes

Biguanide
Biguanides
P-Glycoprotein Inhibitors
Sodium-Glucose Cotransporter 2 Inhibitor
Sodium-Glucose Transporter 2 Inhibitors

Price Statistics

The NADAC for INVOKAMET XR 50-1,000 MG TAB has been published 475 times since Jul 19, 2017, and over the history we have for it it has risen 41.3%. The table below summarizes its recorded NADAC range and movement.

Current price$9.6876 per EA
All-time high$9.6876 (Aug 19, 2026)
All-time low$6.8541 (Jul 19, 2017)
52-week high$9.6876
52-week low$9.5423
Median price$9.1219
Average price$8.7208
Largest weekly change+8.9% (Jan 10, 2018)
Weeks tracked475
Tracking sinceJul 19, 2017

Price History

1W

0.0%

1M

+0.3%

3M

+0.3%

6M

+1.2%

1Y

+1.4%

3Y

+1.1%

5Y

+11.9%

All

+41.3%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 2%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of INVOKAMET XR 50-1,000 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for INVOKAMET XR 50-1,000 MG TAB, manufactured by Janssen Pharmaceuticals Inc., is $9.6876 per EA (NDC 50458094101), effective Aug 19, 2026.

How has the price of INVOKAMET XR 50-1,000 MG TAB changed over time?

Over the history we have for it, the NADAC for INVOKAMET XR 50-1,000 MG TAB has risen 41.3%. It has been tracked across 475 weekly CMS publications since Jul 19, 2017.

What are the highest and lowest recorded NADAC prices for INVOKAMET XR 50-1,000 MG TAB?

Since Jul 19, 2017, the NADAC for INVOKAMET XR 50-1,000 MG TAB has ranged from a low of $6.8541 (Jul 19, 2017) to a high of $9.6876 (Aug 19, 2026), with a median of $9.1219 per EA.

Are there cheaper alternatives to INVOKAMET XR 50-1,000 MG TAB?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, INVOKAMET 50-1,000 MG TABLET, is $9.5389 per EA — about 2% below INVOKAMET XR 50-1,000 MG TAB.

Who manufactures INVOKAMET XR 50-1,000 MG TAB?

INVOKAMET XR 50-1,000 MG TAB (NDC 50458094101) is labeled by Janssen Pharmaceuticals Inc., and CMS classifies it as a brand product.