Product Information

TOPAMAX 25 MG TABLET is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $6.5600 per EA under NDC 50458063965. Its NADAC has been published 635 times since Nov 28, 2013.

TOPAMAX 25 MG TABLET

topiramate
$6.5600per EA

Strength

25 mg/1

NDC

50458063965

Classification

Brand

Dosage Form

TABLET, COATED

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

TOPIRAMATE

Approval Type

New Drug (NDA)

FDA Application

NDA020505

On Market Since

1/1/1997

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Cytochrome P450 3A4 Inducers
Decreased Central Nervous System Disorganized Electrical Activity

Price Statistics

The NADAC for TOPAMAX 25 MG TABLET has been published 635 times since Nov 28, 2013, and over the history we have for it it has risen 86.4%. The table below summarizes its recorded NADAC range and movement.

Current price$6.5600 per EA
All-time high$6.5898 (Jun 10, 2026)
All-time low$3.5185 (Nov 28, 2013)
52-week high$6.5898
52-week low$6.3793
Median price$5.8277
Average price$5.4987
Largest weekly change+9.9% (Jan 14, 2015)
Weeks tracked635
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

-0.5%

3M

-0.2%

6M

+2.8%

1Y

+2.6%

3Y

+5.2%

5Y

+8.7%

All

+86.4%

Generic Alternatives

The matcher finds 8 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 8 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 100% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of TOPAMAX 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for TOPAMAX 25 MG TABLET, manufactured by Janssen Pharmaceuticals Inc., is $6.5600 per EA (NDC 50458063965), effective Jun 24, 2026.

How has the price of TOPAMAX 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for TOPAMAX 25 MG TABLET has risen 86.4%. It has been tracked across 635 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for TOPAMAX 25 MG TABLET?

Since Nov 28, 2013, the NADAC for TOPAMAX 25 MG TABLET has ranged from a low of $3.5185 (Nov 28, 2013) to a high of $6.5898 (Jun 10, 2026), with a median of $5.8277 per EA.

Are there cheaper alternatives to TOPAMAX 25 MG TABLET?

Yes. 8 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, TOPIRAMATE 25 MG TABLET, is $0.0254 per EA — about 100% below TOPAMAX 25 MG TABLET.

Who manufactures TOPAMAX 25 MG TABLET?

TOPAMAX 25 MG TABLET (NDC 50458063965) is labeled by Janssen Pharmaceuticals Inc., and CMS classifies it as a brand product.