Product Information

POLYTUSSIN DM 7.5-5-12.5 MG/5 ML is a generic product labeled by Poly Pharmaceuticals, Inc., priced at $0.0623 per ML under NDC 50991013216. Its NADAC has been published 136 times since Nov 22, 2023.

POLYTUSSIN DM 7.5-5-12.5 MG/5 ML

Dextromethorphan HBr, Phenylephrine HCl, Pyrilamine Maleate
$0.0623per ML
OTC

Strength

7.5; 5; 12.5 mg/5mL; mg/5mL; mg/5mL

NDC

50991013216

Classification

Generic

Dosage Form

SYRUP

Route

ORAL

Last Updated

1/21/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

6/8/2023

Pharmacological Classes

Adrenergic alpha1-Agonists
Sigma-1 Agonist
Sigma-1 Receptor Agonists
Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Uncompetitive NMDA Receptor Antagonists
alpha-1 Adrenergic Agonist

Price Statistics

The NADAC for POLYTUSSIN DM 7.5-5-12.5 MG/5 ML has been published 136 times since Nov 22, 2023, and over the history we have for it it has risen 10.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0623 per ML
All-time high$0.0697 (Sep 10, 2025)
All-time low$0.0566 (Nov 22, 2023)
52-week high$0.0697
52-week low$0.0623
Median price$0.0624
Average price$0.0630
Largest weekly change+10.9% (Mar 19, 2025)
Weeks tracked136
Tracking sinceNov 22, 2023

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

-10.3%

3Y

N/A

5Y

N/A

All

+10.1%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the Dextromethorphan HBr, Phenylephrine HCl, Pyrilamine Maleate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of POLYTUSSIN DM 7.5-5-12.5 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for POLYTUSSIN DM 7.5-5-12.5 MG/5 ML, manufactured by Poly Pharmaceuticals, Inc., is $0.0623 per ML (NDC 50991013216), effective Jun 24, 2026.

How has the price of POLYTUSSIN DM 7.5-5-12.5 MG/5 ML changed over time?

Over the history we have for it, the NADAC for POLYTUSSIN DM 7.5-5-12.5 MG/5 ML has risen 10.1%. It has been tracked across 136 weekly CMS publications since Nov 22, 2023.

What are the highest and lowest recorded NADAC prices for POLYTUSSIN DM 7.5-5-12.5 MG/5 ML?

Since Nov 22, 2023, the NADAC for POLYTUSSIN DM 7.5-5-12.5 MG/5 ML has ranged from a low of $0.0566 (Nov 22, 2023) to a high of $0.0697 (Sep 10, 2025), with a median of $0.0624 per ML.

Are there cheaper alternatives to POLYTUSSIN DM 7.5-5-12.5 MG/5 ML?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of POLYTUSSIN DM 7.5-5-12.5 MG/5 ML, so no direct lower-cost alternative is listed.

Who manufactures POLYTUSSIN DM 7.5-5-12.5 MG/5 ML?

POLYTUSSIN DM 7.5-5-12.5 MG/5 ML (NDC 50991013216) is labeled by Poly Pharmaceuticals, Inc., and CMS classifies it as a generic product.