Product Information

METOLAZONE 2.5 MG TABLET is a generic product labeled by Mylan Institutional LLC, priced at $0.2279 per EA under NDC 51079002320. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Dec 23, 2003. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METOLAZONE 2.5 MG TABLET

metolazone
$0.2279per EA

Strength

2.5 mg/1

NDC

51079002320

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METOLAZONE

Approval Type

Generic (ANDA)

FDA Application

ANDA076698

FDA Approved

12/23/2003

TE Code

AB

On Market Since

4/15/2005

Pharmacological Classes

Increased Diuresis
Thiazide-like Diuretic

Price Statistics

The NADAC for METOLAZONE 2.5 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 49.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2279 per EA
All-time high$1.2971 (Jul 15, 2015)
All-time low$0.1833 (Nov 20, 2024)
52-week high$0.2279
52-week low$0.2090
Median price$1.0105
Average price$0.7954
Largest weekly change+62.2% (Jun 25, 2014)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+3.1%

1M

+3.1%

3M

+3.8%

6M

+1.2%

1Y

+0.7%

3Y

-33.3%

5Y

-77.5%

All

-49.1%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METOLAZONE 2.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for METOLAZONE 2.5 MG TABLET, manufactured by Mylan Institutional LLC, is $0.2279 per EA (NDC 51079002320), effective Aug 19, 2026.

How has the price of METOLAZONE 2.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for METOLAZONE 2.5 MG TABLET has declined 49.1%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for METOLAZONE 2.5 MG TABLET?

Since Nov 28, 2013, the NADAC for METOLAZONE 2.5 MG TABLET has ranged from a low of $0.1833 (Nov 20, 2024) to a high of $1.2971 (Jul 15, 2015), with a median of $1.0105 per EA.

Are there cheaper alternatives to METOLAZONE 2.5 MG TABLET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as METOLAZONE 2.5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures METOLAZONE 2.5 MG TABLET?

METOLAZONE 2.5 MG TABLET (NDC 51079002320) is labeled by Mylan Institutional LLC, and CMS classifies it as a generic product.