Product Information

FLUOROURACIL 5% CREAM is a generic product labeled by Mayne Pharma, priced at $0.5965 per GM under NDC 51862036240. Its NADAC has been published 333 times since Feb 12, 2020.

FLUOROURACIL 5% CREAM

FLUOROURACIL
$0.5965per GM

Strength

50 mg/g

Manufacturer

Mayne Pharma

NDC

51862036240

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

FLUOROURACIL

Approval Type

Generic (ANDA)

FDA Application

ANDA077524

On Market Since

12/3/2019

Pharmacological Classes

Nucleic Acid Synthesis Inhibitors
Nucleoside Metabolic Inhibitor

Price Statistics

The NADAC for FLUOROURACIL 5% CREAM has been published 333 times since Feb 12, 2020, and over the history we have for it it has declined 71.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.5965 per GM
All-time high$2.1046 (Feb 12, 2020)
All-time low$0.5918 (May 20, 2026)
52-week high$0.7382
52-week low$0.5918
Median price$0.8581
Average price$1.1143
Largest weekly change+30.8% (Nov 22, 2023)
Weeks tracked333
Tracking sinceFeb 12, 2020

Price History

1W

0.0%

1M

+0.8%

3M

-0.6%

6M

-3.3%

1Y

-16.2%

3Y

-16.0%

5Y

-67.0%

All

-71.7%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of FLUOROURACIL 5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for FLUOROURACIL 5% CREAM, manufactured by Mayne Pharma, is $0.5965 per GM (NDC 51862036240), effective Jun 24, 2026.

How has the price of FLUOROURACIL 5% CREAM changed over time?

Over the history we have for it, the NADAC for FLUOROURACIL 5% CREAM has declined 71.7%. It has been tracked across 333 weekly CMS publications since Feb 12, 2020.

What are the highest and lowest recorded NADAC prices for FLUOROURACIL 5% CREAM?

Since Feb 12, 2020, the NADAC for FLUOROURACIL 5% CREAM has ranged from a low of $0.5918 (May 20, 2026) to a high of $2.1046 (Feb 12, 2020), with a median of $0.8581 per GM.

Are there cheaper alternatives to FLUOROURACIL 5% CREAM?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as FLUOROURACIL 5% CREAM, but none are currently priced below it.

Who manufactures FLUOROURACIL 5% CREAM?

FLUOROURACIL 5% CREAM (NDC 51862036240) is labeled by Mayne Pharma, and CMS classifies it as a generic product.