Product Information
NAPROXEN-ESOMEPRAZ DR 500-20 MG is a generic product labeled by Dr. Reddy's Laboratories Inc., priced at $2.4703 per EA under NDC 55111070160. Its NADAC has been published 310 times since Jul 22, 2020.
Strength
20; 500 mg/1; mg/1
Manufacturer
Dr. Reddy's Laboratories Inc.NDC
55111070160
Classification
Generic
Dosage Form
TABLET, DELAYED RELEASE
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
ESOMEPRAZOLE MAGNESIUM; NAPROXENApproval Type
Generic (ANDA)
FDA Application
ANDA204206On Market Since
2/18/2020
Pharmacological Classes
Price Statistics
The NADAC for NAPROXEN-ESOMEPRAZ DR 500-20 MG has been published 310 times since Jul 22, 2020, and over the history we have for it it has declined 88.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.4703 per EA |
|---|---|
| All-time high | $25.1793 (Sep 16, 2020) |
| All-time low | $2.3441 (Oct 22, 2025) |
| 52-week high | $3.0530 |
| 52-week low | $2.3441 |
| Median price | $5.3831 |
| Average price | $9.9211 |
| Largest weekly change | -39.8% (Mar 22, 2023) |
| Weeks tracked | 310 |
| Tracking since | Jul 22, 2020 |
Generic Alternatives
The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of NAPROXEN-ESOMEPRAZ DR 500-20 MG?
The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN-ESOMEPRAZ DR 500-20 MG, manufactured by Dr. Reddy's Laboratories Inc., is $2.4703 per EA (NDC 55111070160), effective Jun 24, 2026.
How has the price of NAPROXEN-ESOMEPRAZ DR 500-20 MG changed over time?
Over the history we have for it, the NADAC for NAPROXEN-ESOMEPRAZ DR 500-20 MG has declined 88.2%. It has been tracked across 310 weekly CMS publications since Jul 22, 2020.
What are the highest and lowest recorded NADAC prices for NAPROXEN-ESOMEPRAZ DR 500-20 MG?
Since Jul 22, 2020, the NADAC for NAPROXEN-ESOMEPRAZ DR 500-20 MG has ranged from a low of $2.3441 (Oct 22, 2025) to a high of $25.1793 (Sep 16, 2020), with a median of $5.3831 per EA.
Are there cheaper alternatives to NAPROXEN-ESOMEPRAZ DR 500-20 MG?
2 NADAC-published products share the same active ingredient, strength, and dosage form as NAPROXEN-ESOMEPRAZ DR 500-20 MG, but none are currently priced below it.
Who manufactures NAPROXEN-ESOMEPRAZ DR 500-20 MG?
NAPROXEN-ESOMEPRAZ DR 500-20 MG (NDC 55111070160) is labeled by Dr. Reddy's Laboratories Inc., and CMS classifies it as a generic product.
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Same classification