Product Information
CODEINE-GUAIFEN 10-100 MG/5 ML is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0588 per ML under NDC 58657050004. Its NADAC has been published 598 times since Apr 22, 2015.
Strength
10; 100 mg/5mL; mg/5mL
Manufacturer
Method Pharmaceuticals LLCNDC
58657050004
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CODEINE PHOSPHATE; GUAIFENESINApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
4/1/2014
Pharmacological Classes
Price Statistics
The NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has been published 598 times since Apr 22, 2015, and over the history we have for it it has risen 11.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0588 per ML |
|---|---|
| All-time high | $0.0703 (Jan 10, 2018) |
| All-time low | $0.0204 (Nov 23, 2022) |
| 52-week high | $0.0588 |
| 52-week low | $0.0533 |
| Median price | $0.0497 |
| Average price | $0.0502 |
| Largest weekly change | +124.1% (Jan 18, 2023) |
| Weeks tracked | 598 |
| Tracking since | Apr 22, 2015 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 44% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Method Pharmaceuticals LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Codeine Phosphate and Guaifenesin market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Expectorant class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CODEINE-GUAIFEN 10-100 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for CODEINE-GUAIFEN 10-100 MG/5 ML, manufactured by Method Pharmaceuticals LLC, is $0.0588 per ML (NDC 58657050004), effective Sep 30, 2026.
How has the price of CODEINE-GUAIFEN 10-100 MG/5 ML changed over time?
Over the history we have for it, the NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has risen 11.2%. It has been tracked across 598 weekly CMS publications since Apr 22, 2015.
What are the highest and lowest recorded NADAC prices for CODEINE-GUAIFEN 10-100 MG/5 ML?
Since Apr 22, 2015, the NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has ranged from a low of $0.0204 (Nov 23, 2022) to a high of $0.0703 (Jan 10, 2018), with a median of $0.0497 per ML.
Are there cheaper alternatives to CODEINE-GUAIFEN 10-100 MG/5 ML?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CODEINE-GUAIFEN 10-100 MG/5 ML, is $0.0327 per ML — about 44% below CODEINE-GUAIFEN 10-100 MG/5 ML.
Who manufactures CODEINE-GUAIFEN 10-100 MG/5 ML?
CODEINE-GUAIFEN 10-100 MG/5 ML (NDC 58657050004) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.