Product Information

CODEINE-GUAIFEN 10-100 MG/5 ML is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0543 per ML under NDC 58657050004. Its NADAC has been published 584 times since Apr 22, 2015.

CODEINE-GUAIFEN 10-100 MG/5 ML

Codeine Phosphate and Guaifenesin
$0.0543per ML
OTC
DEA Schedule CIII

Strength

10; 100 mg/5mL; mg/5mL

NDC

58657050004

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Last Updated

6/17/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

4/1/2014

Pharmacological Classes

Decreased Respiratory Secretion Viscosity
Expectorant
Full Opioid Agonists
Increased Respiratory Secretions
Opioid Agonist

Price Statistics

The NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has been published 584 times since Apr 22, 2015, and over the history we have for it it has risen 2.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0543 per ML
All-time high$0.0703 (Jan 10, 2018)
All-time low$0.0204 (Nov 23, 2022)
52-week high$0.0580
52-week low$0.0533
Median price$0.0493
Average price$0.0501
Largest weekly change+124.1% (Jan 18, 2023)
Weeks tracked584
Tracking sinceApr 22, 2015

Price History

1W

0.0%

1M

+1.9%

3M

-2.8%

6M

-0.5%

1Y

-6.2%

3Y

+20.8%

5Y

+1.1%

All

+2.7%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 40% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CODEINE-GUAIFEN 10-100 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for CODEINE-GUAIFEN 10-100 MG/5 ML, manufactured by Method Pharmaceuticals LLC, is $0.0543 per ML (NDC 58657050004), effective Jun 24, 2026.

How has the price of CODEINE-GUAIFEN 10-100 MG/5 ML changed over time?

Over the history we have for it, the NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has risen 2.7%. It has been tracked across 584 weekly CMS publications since Apr 22, 2015.

What are the highest and lowest recorded NADAC prices for CODEINE-GUAIFEN 10-100 MG/5 ML?

Since Apr 22, 2015, the NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has ranged from a low of $0.0204 (Nov 23, 2022) to a high of $0.0703 (Jan 10, 2018), with a median of $0.0493 per ML.

Are there cheaper alternatives to CODEINE-GUAIFEN 10-100 MG/5 ML?

Yes. 2 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, CODEINE-GUAIFEN 10-100 MG/5 ML, is $0.0323 per ML — about 40% below CODEINE-GUAIFEN 10-100 MG/5 ML.

Who manufactures CODEINE-GUAIFEN 10-100 MG/5 ML?

CODEINE-GUAIFEN 10-100 MG/5 ML (NDC 58657050004) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.