Product Information

CODEINE-GUAIFEN 10-100 MG/5 ML is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0323 per ML under NDC 58657050016. Its NADAC has been published 617 times since Jul 2, 2014.

CODEINE-GUAIFEN 10-100 MG/5 ML

Codeine Phosphate and Guaifenesin
$0.0323per ML
OTC
DEA Schedule CIII

Strength

10; 100 mg/5mL; mg/5mL

NDC

58657050016

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Last Updated

6/17/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

4/1/2014

Pharmacological Classes

Decreased Respiratory Secretion Viscosity
Expectorant
Full Opioid Agonists
Increased Respiratory Secretions
Opioid Agonist

Price Statistics

The NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has been published 617 times since Jul 2, 2014, and over the history we have for it it has declined 50.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0323 per ML
All-time high$0.0650 (Jul 16, 2014)
All-time low$0.0250 (Dec 22, 2021)
52-week high$0.0339
52-week low$0.0311
Median price$0.0315
Average price$0.0332
Largest weekly change-34.4% (Jul 23, 2014)
Weeks tracked617
Tracking sinceJul 2, 2014

Price History

1W

0.0%

1M

-0.4%

3M

-0.7%

6M

+2.6%

1Y

-4.7%

3Y

+12.9%

5Y

+13.3%

All

-50.3%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CODEINE-GUAIFEN 10-100 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for CODEINE-GUAIFEN 10-100 MG/5 ML, manufactured by Method Pharmaceuticals LLC, is $0.0323 per ML (NDC 58657050016), effective Jun 24, 2026.

How has the price of CODEINE-GUAIFEN 10-100 MG/5 ML changed over time?

Over the history we have for it, the NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has declined 50.3%. It has been tracked across 617 weekly CMS publications since Jul 2, 2014.

What are the highest and lowest recorded NADAC prices for CODEINE-GUAIFEN 10-100 MG/5 ML?

Since Jul 2, 2014, the NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has ranged from a low of $0.0250 (Dec 22, 2021) to a high of $0.0650 (Jul 16, 2014), with a median of $0.0315 per ML.

Are there cheaper alternatives to CODEINE-GUAIFEN 10-100 MG/5 ML?

2 NADAC-published products share the same active ingredient, strength, and dosage form as CODEINE-GUAIFEN 10-100 MG/5 ML, but none are currently priced below it.

Who manufactures CODEINE-GUAIFEN 10-100 MG/5 ML?

CODEINE-GUAIFEN 10-100 MG/5 ML (NDC 58657050016) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.