Product Information

CODEINE-GUAIFEN 10-100 MG/5 ML is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0331 per ML under NDC 58657050016. Its NADAC has been published 625 times since Jul 2, 2014.

CODEINE-GUAIFEN 10-100 MG/5 ML

Codeine Phosphate and Guaifenesin
$0.0331per ML
OTC
DEA Schedule CIII

Strength

10; 100 mg/5mL; mg/5mL

NDC

58657050016

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

4/1/2014

Pharmacological Classes

Decreased Respiratory Secretion Viscosity
Expectorant
Full Opioid Agonists
Increased Respiratory Secretions
Opioid Agonist

Price Statistics

The NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has been published 625 times since Jul 2, 2014, and over the history we have for it it has declined 49.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0331 per ML
All-time high$0.0650 (Jul 16, 2014)
All-time low$0.0250 (Dec 22, 2021)
52-week high$0.0331
52-week low$0.0311
Median price$0.0316
Average price$0.0332
Largest weekly change-34.4% (Jul 23, 2014)
Weeks tracked625
Tracking sinceJul 2, 2014

Price History

1W

+1.8%

1M

+1.8%

3M

+2.0%

6M

+3.7%

1Y

+2.2%

3Y

+5.0%

5Y

+21.5%

All

-49.1%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CODEINE-GUAIFEN 10-100 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for CODEINE-GUAIFEN 10-100 MG/5 ML, manufactured by Method Pharmaceuticals LLC, is $0.0331 per ML (NDC 58657050016), effective Aug 19, 2026.

How has the price of CODEINE-GUAIFEN 10-100 MG/5 ML changed over time?

Over the history we have for it, the NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has declined 49.1%. It has been tracked across 625 weekly CMS publications since Jul 2, 2014.

What are the highest and lowest recorded NADAC prices for CODEINE-GUAIFEN 10-100 MG/5 ML?

Since Jul 2, 2014, the NADAC for CODEINE-GUAIFEN 10-100 MG/5 ML has ranged from a low of $0.0250 (Dec 22, 2021) to a high of $0.0650 (Jul 16, 2014), with a median of $0.0316 per ML.

Are there cheaper alternatives to CODEINE-GUAIFEN 10-100 MG/5 ML?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CODEINE-GUAIFEN 10-100 MG/5 ML in a comparable dosage form, but none are currently priced below it.

Who manufactures CODEINE-GUAIFEN 10-100 MG/5 ML?

CODEINE-GUAIFEN 10-100 MG/5 ML (NDC 58657050016) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.