Product Information

GUAIFENESIN-DM 100-10 MG/5 ML is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0231 per ML under NDC 58657050408. Its NADAC has been published 97 times since Jun 12, 2024.

GUAIFENESIN-DM 100-10 MG/5 ML

Guaifenesin and Dextromethorphan Hydrobromide
$0.0231per ML
OTC

Strength

10; 100 mg/5mL; mg/5mL

NDC

58657050408

Classification

Generic

Dosage Form

SYRUP

Route

ORAL

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

4/1/2024

Pharmacological Classes

Decreased Respiratory Secretion Viscosity
Expectorant
Increased Respiratory Secretions
Sigma-1 Agonist
Sigma-1 Receptor Agonists
Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Uncompetitive NMDA Receptor Antagonists

Price Statistics

The NADAC for GUAIFENESIN-DM 100-10 MG/5 ML has been published 97 times since Jun 12, 2024, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$0.0231 per ML
All-time high$0.0252 (Aug 12, 2026)
All-time low$0.0221 (Jul 17, 2024)
52-week high$0.0252
52-week low$0.0231
Median price$0.0242
Average price$0.0242
Largest weekly change-8.2% (Aug 19, 2026)
Weeks tracked97
Tracking sinceJun 12, 2024

Price History

1W

-8.2%

1M

-8.2%

3M

-8.2%

6M

-7.0%

1Y

-4.4%

3Y

N/A

5Y

N/A

All

-1.5%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of GUAIFENESIN-DM 100-10 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for GUAIFENESIN-DM 100-10 MG/5 ML, manufactured by Method Pharmaceuticals LLC, is $0.0231 per ML (NDC 58657050408), effective Aug 19, 2026.

How has the price of GUAIFENESIN-DM 100-10 MG/5 ML changed over time?

Over the history we have for it, the NADAC for GUAIFENESIN-DM 100-10 MG/5 ML has held within roughly two percent of its current level. It has been tracked across 97 weekly CMS publications since Jun 12, 2024.

What are the highest and lowest recorded NADAC prices for GUAIFENESIN-DM 100-10 MG/5 ML?

Since Jun 12, 2024, the NADAC for GUAIFENESIN-DM 100-10 MG/5 ML has ranged from a low of $0.0221 (Jul 17, 2024) to a high of $0.0252 (Aug 12, 2026), with a median of $0.0242 per ML.

Are there cheaper alternatives to GUAIFENESIN-DM 100-10 MG/5 ML?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as GUAIFENESIN-DM 100-10 MG/5 ML in a comparable dosage form, but none are currently priced below it.

Who manufactures GUAIFENESIN-DM 100-10 MG/5 ML?

GUAIFENESIN-DM 100-10 MG/5 ML (NDC 58657050408) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.