Product Information

GUAIFENESIN-DM 100-10 MG/5 ML is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0252 per ML under NDC 58657050508. Its NADAC has been published 489 times since Oct 12, 2016.

GUAIFENESIN-DM 100-10 MG/5 ML

Guaifenesin and Dextromethorphan Hydrobromide
$0.0252per ML
OTC

Strength

10; 100 mg/5mL; mg/5mL

NDC

58657050508

Classification

Generic

Dosage Form

SYRUP

Route

ORAL

Last Updated

4/22/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

6/14/2016

Pharmacological Classes

Decreased Respiratory Secretion Viscosity
Expectorant
Increased Respiratory Secretions
Sigma-1 Agonist
Sigma-1 Receptor Agonists
Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Uncompetitive NMDA Receptor Antagonists

Price Statistics

The NADAC for GUAIFENESIN-DM 100-10 MG/5 ML has been published 489 times since Oct 12, 2016, and over the history we have for it it has risen 213.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0252 per ML
All-time high$0.0307 (Apr 10, 2024)
All-time low$0.0080 (Oct 12, 2016)
52-week high$0.0252
52-week low$0.0242
Median price$0.0123
Average price$0.0161
Largest weekly change+53.5% (Sep 21, 2022)
Weeks tracked489
Tracking sinceOct 12, 2016

Price History

1W

0.0%

1M

0.0%

3M

+1.4%

6M

+4.1%

1Y

+4.1%

3Y

+0.9%

5Y

+116.2%

All

+213.1%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of GUAIFENESIN-DM 100-10 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for GUAIFENESIN-DM 100-10 MG/5 ML, manufactured by Method Pharmaceuticals LLC, is $0.0252 per ML (NDC 58657050508), effective Jun 24, 2026.

How has the price of GUAIFENESIN-DM 100-10 MG/5 ML changed over time?

Over the history we have for it, the NADAC for GUAIFENESIN-DM 100-10 MG/5 ML has risen 213.1%. It has been tracked across 489 weekly CMS publications since Oct 12, 2016.

What are the highest and lowest recorded NADAC prices for GUAIFENESIN-DM 100-10 MG/5 ML?

Since Oct 12, 2016, the NADAC for GUAIFENESIN-DM 100-10 MG/5 ML has ranged from a low of $0.0080 (Oct 12, 2016) to a high of $0.0307 (Apr 10, 2024), with a median of $0.0123 per ML.

Are there cheaper alternatives to GUAIFENESIN-DM 100-10 MG/5 ML?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as GUAIFENESIN-DM 100-10 MG/5 ML, but none are currently priced below it.

Who manufactures GUAIFENESIN-DM 100-10 MG/5 ML?

GUAIFENESIN-DM 100-10 MG/5 ML (NDC 58657050508) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.