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Product Information

BELBUCA 450 MCG FILM is a brand product labeled by BioDelivery Sciences International Inc, priced at $16.1293 per EA under NDC 59385002460. Its NADAC has been published 464 times since Oct 4, 2017.

FDA first approved this application on Oct 23, 2015.

BELBUCA 450 MCG FILM

buprenorphine hydrochloride
$16.1293per EA
DEA Schedule CIII

Strength

450 ug/1

NDC

59385002460

Classification

Brand

Dosage Form

FILM, SOLUBLE

Route

BUCCAL

Effective Date

8/19/2026

Active Ingredients

BUPRENORPHINE HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA207932

FDA Approved

10/23/2015

On Market Since

8/21/2017

Pharmacological Classes

Partial Opioid Agonist
Partial Opioid Agonists

Price Statistics

The NADAC for BELBUCA 450 MCG FILM has been published 464 times since Oct 4, 2017, and over the history we have for it it has risen 69.2%. The table below summarizes its recorded NADAC range and movement.

Current price$16.1293 per EA
All-time high$16.1392 (Aug 12, 2026)
All-time low$9.4950 (Jan 17, 2018)
52-week high$16.1392
52-week low$15.3537
Median price$13.1273
Average price$12.9761
Largest weekly change+9.4% (Mar 20, 2019)
Weeks tracked464
Tracking sinceOct 4, 2017

Price History

1W

-0.1%

1M

-0.1%

3M

+0.1%

6M

+0.0%

1Y

+4.9%

3Y

+17.0%

5Y

+29.0%

All

+69.2%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the buprenorphine hydrochloride market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Same classification

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ZUBSOLV 5.7-1.4 MG TABLET SL
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$10.5462
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ZUBSOLV 8.6-2.1 MG TABLET SL
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$15.8138
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$17.1655
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ZUBSOLV 11.4-2.9 MG TABLET SL
Brand
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$21.0524
per EA

Frequently asked questions

What is the NADAC price of BELBUCA 450 MCG FILM?

The current National Average Drug Acquisition Cost (NADAC) for BELBUCA 450 MCG FILM, manufactured by BioDelivery Sciences International Inc, is $16.1293 per EA (NDC 59385002460), effective Aug 19, 2026.

How has the price of BELBUCA 450 MCG FILM changed over time?

Over the history we have for it, the NADAC for BELBUCA 450 MCG FILM has risen 69.2%. It has been tracked across 464 weekly CMS publications since Oct 4, 2017.

What are the highest and lowest recorded NADAC prices for BELBUCA 450 MCG FILM?

Since Oct 4, 2017, the NADAC for BELBUCA 450 MCG FILM has ranged from a low of $9.4950 (Jan 17, 2018) to a high of $16.1392 (Aug 12, 2026), with a median of $13.1273 per EA.

Are there cheaper alternatives to BELBUCA 450 MCG FILM?

No other NADAC-published product currently shares the active ingredient and strength of BELBUCA 450 MCG FILM in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures BELBUCA 450 MCG FILM?

BELBUCA 450 MCG FILM (NDC 59385002460) is labeled by BioDelivery Sciences International Inc, and CMS classifies it as a brand product.