Product Information
BELBUCA 450 MCG FILM is a brand product labeled by BioDelivery Sciences International Inc, priced at $16.1268 per EA under NDC 59385002460. Its NADAC has been published 456 times since Oct 4, 2017.
Strength
450 ug/1
Manufacturer
BioDelivery Sciences International IncNDC
59385002460
Classification
Brand
Dosage Form
FILM, SOLUBLE
Route
BUCCAL
Last Updated
6/17/2026
Active Ingredients
BUPRENORPHINE HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA207932On Market Since
8/21/2017
Pharmacological Classes
Price Statistics
The NADAC for BELBUCA 450 MCG FILM has been published 456 times since Oct 4, 2017, and over the history we have for it it has risen 69.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $16.1268 per EA |
|---|---|
| All-time high | $16.1268 (Jun 24, 2026) |
| All-time low | $9.4950 (Jan 17, 2018) |
| 52-week high | $16.1268 |
| 52-week low | $15.3537 |
| Median price | $13.1273 |
| Average price | $12.9207 |
| Largest weekly change | +9.4% (Mar 20, 2019) |
| Weeks tracked | 456 |
| Tracking since | Oct 4, 2017 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the buprenorphine hydrochloride market page.
Lowest-Cost Alternatives
No alternatives available
Frequently asked questions
What is the NADAC price of BELBUCA 450 MCG FILM?
The current National Average Drug Acquisition Cost (NADAC) for BELBUCA 450 MCG FILM, manufactured by BioDelivery Sciences International Inc, is $16.1268 per EA (NDC 59385002460), effective Jun 24, 2026.
How has the price of BELBUCA 450 MCG FILM changed over time?
Over the history we have for it, the NADAC for BELBUCA 450 MCG FILM has risen 69.1%. It has been tracked across 456 weekly CMS publications since Oct 4, 2017.
What are the highest and lowest recorded NADAC prices for BELBUCA 450 MCG FILM?
Since Oct 4, 2017, the NADAC for BELBUCA 450 MCG FILM has ranged from a low of $9.4950 (Jan 17, 2018) to a high of $16.1268 (Jun 24, 2026), with a median of $13.1273 per EA.
Are there cheaper alternatives to BELBUCA 450 MCG FILM?
No other NADAC-published product currently shares the active ingredient, strength, and dosage form of BELBUCA 450 MCG FILM, so no direct lower-cost alternative is listed.
Who manufactures BELBUCA 450 MCG FILM?
BELBUCA 450 MCG FILM (NDC 59385002460) is labeled by BioDelivery Sciences International Inc, and CMS classifies it as a brand product.
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