Therapeutic Classes/Partial Opioid Agonist

Partial Opioid Agonist

104 drugs across 23 manufacturers|82 Generic,22 Brand

The Partial Opioid Agonist class contains 104 NDCs from 23 manufacturers (82 generic, 22 brand), at an average NADAC of $16.35 per unit. Every drug, manufacturer, and price in this FDA-defined pharmacologic class is listed below.

Total Drugs

104

82G / 22B

Manufacturers

Avg $16.3485/unit

Avg 7d Change

+0.74%

Across 98 drugs with changes

7d Activity

71↑27↓6 flat

of 104 total drugs

Class Price Trend

Monthly average NADAC price per unit, split by generic and brand

Manufacturer Breakdown

23 manufacturers producing drugs in this therapeutic class(1 pricing outlier)

Rhodes Pharmaceuticals L.P.

9 drugs

$23.1444

avg/unit

Ingenus Pharmaceuticals LLC

BioDelivery Sciences International Inc

Teva Pharmaceuticals USA Inc.

5 drugs

$41.2535

avg/unit

Amneal Pharmaceuticals NY LLC

Mylan Pharmaceuticals Inc.

4 drugs

$2.6074

avg/unit

Dr. Reddy's Laboratories Inc.

4 drugs

$2.6074

avg/unit

Hikma Pharmaceuticals USA Inc.

4 drugs

$0.5081

avg/unit

and 11 more manufacturers

Drug Portfolio

104 drugs total, 104 shown

Drug ↕	NDC	Price	7d Change ↕	Class	Market Outlier	Manufacturer ↕
BUTRANS 20 MCG/HR PATCH buprenorphine	59011075204	$131.0939 per EA	+0.02%	Brand	—	Purdue Pharma LP
BUTRANS 15 MCG/HR PATCH buprenorphine	59011075804	$124.6231 per EA	+0.01%	Brand	—	Purdue Pharma LP
BUTRANS 10 MCG/HR PATCH buprenorphine	59011075104	$73.6002 per EA	-0.03%	Brand	—	Purdue Pharma LP
BUTRANS 7.5 MCG/HR PATCH buprenorphine	59011075704	$68.8220 per EA	+0.12%	Brand	—	Purdue Pharma LP
BUPRENORPHINE 20 MCG/HR PATCH Buprenorphine	00093365940	$58.8288 per EA	+2.64%	Generic	—	Teva Pharmaceuticals USA Inc.
BUPRENORPHINE 20 MCG/HR PATCH Buprenorphine	42858083940	$58.8288 per EA	+2.64%	Generic	—	Rhodes Pharmaceuticals L.P.
BUPRENORPHINE 20 MCG/HR PATCH buprenorphine	47781040804	$58.8288 per EA	+2.64%	Generic	—	Alvogen Inc.
BUPRENORPHINE 20 MCG/HR PATCH Buprenorphine	50742037604	$58.8288 per EA	+2.64%	Generic	—	Ingenus Pharmaceuticals LLC
BUPRENORPHINE 20 MCG/HR PATCH Buprenorphine	69238120502	$58.8288 per EA	+2.64%	Generic	—	Amneal Pharmaceuticals NY LLC
BUPRENORPHINE 15 MCG/HR PATCH Buprenorphine	00093365840	$53.7821 per EA	+2.06%	Generic	—	Teva Pharmaceuticals USA Inc.
BUPRENORPHINE 15 MCG/HR PATCH Buprenorphine	42858058640	$53.7821 per EA	+2.06%	Generic	—	Rhodes Pharmaceuticals L.P.
BUPRENORPHINE 15 MCG/HR PATCH Buprenorphine	50742037504	$53.7821 per EA	+2.06%	Generic	—	Ingenus Pharmaceuticals LLC
BUPRENORPHINE 15 MCG/HR PATCH Buprenorphine	69238120402	$53.7821 per EA	+2.06%	Generic	—	Amneal Pharmaceuticals NY LLC
BUPRENORPHINE 15 MCG/HR PATCH buprenorphine	47781041904	$50.1598 per EA	—	Generic	—	Alvogen Inc.
BUTRANS 5 MCG/HR PATCH buprenorphine	59011075004	$48.8659 per EA	0.00%	Brand	—	Purdue Pharma LP
BUPRENORPHINE 7.5 MCG/HR PATCH Buprenorphine	00093323940	$37.6788 per EA	-0.45%	Generic	—	Teva Pharmaceuticals USA Inc.
BUPRENORPHINE 7.5 MCG/HR PATCH Buprenorphine	42858035340	$37.6788 per EA	-0.45%	Generic	—	Rhodes Pharmaceuticals L.P.
BUPRENORPHINE 7.5 MCG/HR PATCH Buprenorphine	50742037304	$37.6788 per EA	-0.45%	Generic	—	Ingenus Pharmaceuticals LLC
BUPRENORPHINE 7.5 MCG/HR PATCH Buprenorphine	69238150502	$37.6788 per EA	-0.45%	Generic	—	Amneal Pharmaceuticals NY LLC
BUPRENORPHINE 10 MCG/HR PATCH Buprenorphine	00093365740	$32.5293 per EA	-3.62%	Generic	—	Teva Pharmaceuticals USA Inc.
BUPRENORPHINE 10 MCG/HR PATCH Buprenorphine	42858049340	$32.5293 per EA	-3.62%	Generic	—	Rhodes Pharmaceuticals L.P.
BUPRENORPHINE 10 MCG/HR PATCH Buprenorphine	50742037404	$32.5293 per EA	-3.62%	Generic	—	Ingenus Pharmaceuticals LLC
BUPRENORPHINE 10 MCG/HR PATCH Buprenorphine	69238120302	$32.5293 per EA	-3.62%	Generic	—	Amneal Pharmaceuticals NY LLC
BUPRENORPHINE 10 MCG/HR PATCH buprenorphine	47781040704	$30.1705 per EA	—	Generic	—	Alvogen Inc.
BUPRENORPHINE 5 MCG/HR PATCH Buprenorphine	00093365640	$23.4485 per EA	-1.55%	Generic	—	Teva Pharmaceuticals USA Inc.
BUPRENORPHINE 5 MCG/HR PATCH Buprenorphine	42858075040	$23.4485 per EA	-1.55%	Generic	—	Rhodes Pharmaceuticals L.P.
BUPRENORPHINE 5 MCG/HR PATCH Buprenorphine	50742037204	$23.4485 per EA	-1.55%	Generic	—	Ingenus Pharmaceuticals LLC
BUPRENORPHINE 5 MCG/HR PATCH Buprenorphine	69238120202	$23.4485 per EA	-1.55%	Generic	—	Amneal Pharmaceuticals NY LLC
ZUBSOLV 11.4-2.9 MG TABLET SL buprenorphine hydrochloride and naloxone hydrochloride	54123011430	$21.0479 per EA	-0.02%	Brand	—	Orexo US, Inc.
BUPRENORPHINE 5 MCG/HR PATCH buprenorphine	47781040604	$20.9308 per EA	—	Generic	—	Alvogen Inc.
BELBUCA 900 MCG FILM buprenorphine hydrochloride	59385002760	$18.5906 per EA	-0.03%	Brand	—	BioDelivery Sciences International Inc
BELBUCA 750 MCG FILM buprenorphine hydrochloride	59385002660	$18.0990 per EA	+0.02%	Brand	—	BioDelivery Sciences International Inc
BELBUCA 600 MCG FILM buprenorphine hydrochloride	59385002560	$17.1903 per EA	-0.08%	Brand	—	BioDelivery Sciences International Inc
SUBOXONE 12 MG-3 MG SL FILM buprenorphine hydrochloride, naloxone hydrochloride	12496121203	$17.1632 per EA	-0.01%	Brand	—	Indivior Inc.
BELBUCA 450 MCG FILM buprenorphine hydrochloride	59385002460	$16.1142 per EA	-0.09%	Brand	—	BioDelivery Sciences International Inc
ZUBSOLV 8.6-2.1 MG TABLET SL buprenorphine hydrochloride and naloxone hydrochloride	54123098630	$15.8095 per EA	-0.03%	Brand	—	Orexo US, Inc.
BELBUCA 300 MCG FILM buprenorphine hydrochloride	59385002360	$11.8563 per EA	+0.06%	Brand	—	BioDelivery Sciences International Inc
ZUBSOLV 5.7-1.4 MG TABLET SL buprenorphine hydrochloride and naloxone hydrochloride	54123095730	$10.5431 per EA	-0.03%	Brand	—	Orexo US, Inc.
ZUBSOLV 2.9-0.71 MG TABLET SL buprenorphine hydrochloride and naloxone hydrochloride	54123092930	$10.5186 per EA	-0.05%	Brand	—	Orexo US, Inc.
SUBOXONE 8 MG-2 MG SL FILM buprenorphine hydrochloride, naloxone hydrochloride	12496120803	$8.5922 per EA	-0.02%	Brand	—	Indivior Inc.
SUBOXONE 4 MG-1 MG SL FILM buprenorphine hydrochloride, naloxone hydrochloride	12496120403	$8.5844 per EA	0.00%	Brand	—	Indivior Inc.
BELBUCA 150 MCG FILM buprenorphine hydrochloride	59385002260	$7.5576 per EA	+0.05%	Brand	—	BioDelivery Sciences International Inc
BELBUCA 75 MCG FILM buprenorphine hydrochloride	59385002160	$7.5417 per EA	+0.02%	Brand	—	BioDelivery Sciences International Inc
ZUBSOLV 1.4-0.36 MG TABLET SL buprenorphine hydrochloride and naloxone hydrochloride	54123091430	$5.2646 per EA	+0.03%	Brand	—	Orexo US, Inc.
ZUBSOLV 0.7-0.18 MG TABLET SL buprenorphine hydrochloride and naloxone hydrochloride	54123090730	$5.2614 per EA	-0.04%	Brand	—	Orexo US, Inc.
SUBOXONE 2 MG-0.5 MG SL FILM buprenorphine hydrochloride, naloxone hydrochloride	12496120203	$4.7852 per EA	0.00%	Brand	—	Indivior Inc.
BUPRENORPHINE-NALOXONE 12-3 MG SL FILM Buprenorphine and Naloxone	00378876893	$4.4856 per EA	+0.39%	Generic	—	Mylan Pharmaceuticals Inc.
BUPRENORPHINE-NALOXONE 12-3 MG SL FILM Buprenorphine and Naloxone	43598058130	$4.4856 per EA	+0.39%	Generic	—	Dr. Reddy's Laboratories Inc.
BUPRENORPHINE-NALOXONE 12-3 MG SL FILM Buprenorphine and Naloxone	47781035803	$4.4856 per EA	+0.39%	Generic	—	Alvogen Inc.
BUPRENORPHINE-NALOXONE 12-3 MG SL FILM buprenorphine and naloxone	50742036530	$4.4856 per EA	+0.39%	Generic	—	Ingenus Pharmaceuticals LLC
BUPRENORPHINE-NALOXONE 4-1 MG SL FILM Buprenorphine and Naloxone	00378876693	$2.5762 per EA	+1.80%	Generic	—	Mylan Pharmaceuticals Inc.
BUPRENORPHINE-NALOXONE 4-1 MG SL FILM Buprenorphine and Naloxone	43598058030	$2.5762 per EA	+1.80%	Generic	—	Dr. Reddy's Laboratories Inc.
BUPRENORPHINE-NALOXONE 4-1 MG SL FILM Buprenorphine and Naloxone	47781035603	$2.5762 per EA	+1.80%	Generic	—	Alvogen Inc.
BUPRENORPHINE-NALOXONE 4-1 MG SL FILM buprenorphine and naloxone	50742039830	$2.5762 per EA	+1.80%	Generic	—	Ingenus Pharmaceuticals LLC
BUPRENORPHINE-NALOXONE 8-2 MG SL FILM Buprenorphine and Naloxone	00378876793	$1.9823 per EA	-4.44%	Generic	—	Mylan Pharmaceuticals Inc.
BUPRENORPHINE-NALOXONE 8-2 MG SL FILM Buprenorphine and Naloxone	43598058230	$1.9823 per EA	-4.44%	Generic	—	Dr. Reddy's Laboratories Inc.
BUPRENORPHINE-NALOXONE 8-2 MG SL FILM Buprenorphine and Naloxone	47781035703	$1.9823 per EA	-4.44%	Generic	—	Alvogen Inc.
BUPRENORPHINE-NALOXONE 8-2 MG SL FILM buprenorphine and naloxone	50742036430	$1.9823 per EA	-4.44%	Generic	—	Ingenus Pharmaceuticals LLC
BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM Buprenorphine and Naloxone	00378876593	$1.3855 per EA	+0.51%	Generic	—	Mylan Pharmaceuticals Inc.
BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM Buprenorphine and Naloxone	43598057930	$1.3855 per EA	+0.51%	Generic	—	Dr. Reddy's Laboratories Inc.
BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM Buprenorphine and Naloxone	47781035503	$1.3855 per EA	+0.51%	Generic	—	Alvogen Inc.
BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM buprenorphine and naloxone	50742039730	$1.3855 per EA	+0.51%	Generic	—	Ingenus Pharmaceuticals LLC
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET buprenorphine hydrochloride and naloxone hydrochloride dihydrate	00054018913	$0.6628 per EA	+3.91%	Generic	—	Hikma Pharmaceuticals USA Inc.
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET buprenorphine hydrochloride and naloxone hydrochloride	00121203630	$0.6628 per EA	+3.91%	Generic	—	PAI Holdings LLC
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET Buprenorphine and Naloxone	00228315503	$0.6628 per EA	+3.91%	Generic	—	Actavis Pharma, Inc.
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate	00406802003	$0.6628 per EA	+3.91%	Generic	—	SpecGx LLC
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET buprenorphine hydrochloride and naloxone hydrochloride dihydrate	00904701006	$0.6628 per EA	+3.91%	Generic	—	Major Pharmaceuticals
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET BUPRENORPHINE HYDROCHLORIDE and NALOXONE HYDROCHLORIDE DIHYDRATE	16729055010	$0.6628 per EA	+3.91%	Generic	—	Accord Healthcare Inc.
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET Buprenorphine and Naloxone	42858060203	$0.6628 per EA	+3.91%	Generic	—	Rhodes Pharmaceuticals L.P.
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET Buprenorphine and Naloxone	50268014515	$0.6628 per EA	+3.91%	Generic	—	AvPAK
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET Buprenorphine and Naloxone	60687063765	$0.6628 per EA	+3.91%	Generic	—	American Health Packaging
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET Buprenorphine and Naloxone	62175045832	$0.6628 per EA	+3.91%	Generic	—	Lannett Company Inc.
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET Buprenorphine and Naloxone	62756097083	$0.6628 per EA	+3.91%	Generic	—	Sun Pharmaceutical Industries Inc.
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET Buprenorphine and Naloxone	65162041503	$0.6628 per EA	+3.91%	Generic	—	Amneal Pharmaceuticals LLC
BUPRENORPHINE 8 MG TABLET SL Buprenorphine	00054017713	$0.5714 per EA	+0.67%	Generic	—	Hikma Pharmaceuticals USA Inc.
BUPRENORPHINE 8 MG TABLET SL buprenorphine hydrochloride	00121203830	$0.5714 per EA	+0.67%	Generic	—	PAI Holdings LLC
BUPRENORPHINE 8 MG TABLET SL Buprenorphine	00228315303	$0.5714 per EA	+0.67%	Generic	—	Actavis Pharma, Inc.
BUPRENORPHINE 8 MG TABLET SL Buprenorphine	00904715504	$0.5714 per EA	+0.67%	Generic	—	Major Pharmaceuticals
BUPRENORPHINE 8 MG TABLET SL BUPRENORPHINE	42858050203	$0.5714 per EA	+0.67%	Generic	—	Rhodes Pharmaceuticals L.P.
BUPRENORPHINE 8 MG TABLET SL Buprenorphine	50268012915	$0.5714 per EA	+0.67%	Generic	—	AvPAK
BUPRENORPHINE 8 MG TABLET SL Buprenorphine	60687049221	$0.5714 per EA	+0.67%	Generic	—	American Health Packaging
BUPRENORPHINE 8 MG TABLET SL Buprenorphine	62756046083	$0.5714 per EA	+0.67%	Generic	—	Sun Pharmaceutical Industries Inc.
BUPRENORPHINE 8 MG TABLET SL buprenorphine hydrochloride	72888018330	$0.5714 per EA	+0.67%	Generic	—	Advagen Pharma Ltd.
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET buprenorphine hydrochloride and naloxone hydrochloride dihydrate	00054018813	$0.5214 per EA	+12.86%	Generic	—	Hikma Pharmaceuticals USA Inc.
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET buprenorphine hydrochloride and naloxone hydrochloride	00121101830	$0.5214 per EA	+12.86%	Generic	—	PAI Holdings LLC
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET Buprenorphine and Naloxone	00228315403	$0.5214 per EA	+12.86%	Generic	—	Actavis Pharma, Inc.
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate	00406800503	$0.5214 per EA	+12.86%	Generic	—	SpecGx LLC
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET buprenorphine hydrochloride and naloxone hydrochloride dihydrate	00904700906	$0.5214 per EA	+12.86%	Generic	—	Major Pharmaceuticals
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET BUPRENORPHINE HYDROCHLORIDE and NALOXONE HYDROCHLORIDE DIHYDRATE	16729054910	$0.5214 per EA	+12.86%	Generic	—	Accord Healthcare Inc.
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET Buprenorphine and Naloxone	42858060103	$0.5214 per EA	+12.86%	Generic	—	Rhodes Pharmaceuticals L.P.
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET Buprenorphine and Naloxone	50268014415	$0.5214 per EA	+12.86%	Generic	—	AvPAK
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET Buprenorphine and Naloxone	60687062665	$0.5214 per EA	+12.86%	Generic	—	American Health Packaging
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET Buprenorphine and Naloxone	62175045232	$0.5214 per EA	+12.86%	Generic	—	Lannett Company Inc.
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET Buprenorphine and Naloxone	62756096983	$0.5214 per EA	+12.86%	Generic	—	Sun Pharmaceutical Industries Inc.
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET Buprenorphine and Naloxone	65162041603	$0.5214 per EA	+12.86%	Generic	—	Amneal Pharmaceuticals LLC
BUPRENORPHINE 2 MG TABLET SL Buprenorphine	00054017613	$0.2768 per EA	+4.53%	Generic	—	Hikma Pharmaceuticals USA Inc.
BUPRENORPHINE 2 MG TABLET SL buprenorphine hydrochloride	00121101930	$0.2768 per EA	+4.53%	Generic	—	PAI Holdings LLC
BUPRENORPHINE 2 MG TABLET SL Buprenorphine	00228315603	$0.2768 per EA	+4.53%	Generic	—	Actavis Pharma, Inc.
BUPRENORPHINE 2 MG TABLET SL Buprenorphine	00904715404	$0.2768 per EA	+4.53%	Generic	—	Major Pharmaceuticals
BUPRENORPHINE 2 MG TABLET SL BUPRENORPHINE	42858050103	$0.2768 per EA	+4.53%	Generic	—	Rhodes Pharmaceuticals L.P.
BUPRENORPHINE 2 MG TABLET SL Buprenorphine	50268012815	$0.2768 per EA	+4.53%	Generic	—	AvPAK
BUPRENORPHINE 2 MG TABLET SL Buprenorphine	60687048121	$0.2768 per EA	+4.53%	Generic	—	American Health Packaging
BUPRENORPHINE 2 MG TABLET SL Buprenorphine	62756045983	$0.2768 per EA	+4.53%	Generic	—	Sun Pharmaceutical Industries Inc.
BUPRENORPHINE 2 MG TABLET SL buprenorphine hydrochloride	72888018230	$0.2768 per EA	+4.53%	Generic	—	Advagen Pharma Ltd.

Follow this class across the site

These links connect the therapeutic class page to the specific suppliers, markets, and trend surfaces that help users keep exploring.

Top supplier

Rhodes Pharmaceuticals L.P. manufacturer profile

Review the supplier with the strongest product footprint inside this therapeutic class.

Lead market

Buprenorphine market page

Move from the therapeutic class into the molecule that appears most often in this class-specific portfolio.

Trend hub

Latest trend hub

Compare this class against the rest of the weekly NADAC trend surface.

Guide

Understanding NADAC pricing

Use the explainer when you need a plain-English refresher on how these class-level numbers are published and interpreted.

Frequently Asked Questions

How many drugs are in the Partial Opioid Agonist class?

The Partial Opioid Agonist class contains 104 NDCs from 23 manufacturers — 82 generic and 22 brand products.

What is the average price of Partial Opioid Agonist drugs?

The average NADAC for the Partial Opioid Agonist class is $16.3485 per unit across 104 NDCs.

Is generic cheaper than brand in the Partial Opioid Agonist class?

Among products priced per EA, the average generic NADAC in this class is $12.7893, versus $29.6148 for brand — brand products average about 2.3× the generic price.

Which manufacturers make Partial Opioid Agonist drugs?

23 manufacturers make drugs in the Partial Opioid Agonist class. Ranked by number of NDCs, the largest are Rhodes Pharmaceuticals L.P. (9), Ingenus Pharmaceuticals LLC (9), Alvogen Inc. (8), BioDelivery Sciences International Inc (7), Orexo US, Inc. (6).

How has Partial Opioid Agonist pricing changed recently?

Over the past 7 days, 71 NDCs in this class rose and 27 fell, with a class-wide average change of +0.7%.