Product Information
METFORMIN ER 500 MG OSMOTIC TB is a generic product labeled by Aurobindo Pharma Limited, priced at $0.1644 per EA under NDC 59651004260. Its NADAC has been published 44 times since Dec 3, 2025.
FDA first approved this application on Oct 18, 2024. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Aurobindo Pharma LimitedNDC
59651004260
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA209694FDA Approved
10/18/2024
TE Code
AB2
On Market Since
10/18/2024
Pharmacological Classes
Price Statistics
The NADAC for METFORMIN ER 500 MG OSMOTIC TB has been published 44 times since Dec 3, 2025, and over the history we have for it it has risen 6.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1644 per EA |
|---|---|
| All-time high | $0.1644 (Sep 30, 2026) |
| All-time low | $0.1017 (Apr 22, 2026) |
| 52-week high | $0.1644 |
| 52-week low | $0.1017 |
| Median price | $0.1139 |
| Average price | $0.1195 |
| Largest weekly change | +18.9% (Aug 19, 2026) |
| Weeks tracked | 44 |
| Tracking since | Dec 3, 2025 |
Generic Alternatives
The matcher finds 21 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 91% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Aurobindo Pharma Limited manufacturer profile
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Drug market
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Therapeutic class
Biguanide class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METFORMIN ER 500 MG OSMOTIC TB?
The current National Average Drug Acquisition Cost (NADAC) for METFORMIN ER 500 MG OSMOTIC TB, manufactured by Aurobindo Pharma Limited, is $0.1644 per EA (NDC 59651004260), effective Sep 30, 2026.
How has the price of METFORMIN ER 500 MG OSMOTIC TB changed over time?
Over the history we have for it, the NADAC for METFORMIN ER 500 MG OSMOTIC TB has risen 6.7%. It has been tracked across 44 weekly CMS publications since Dec 3, 2025.
What are the highest and lowest recorded NADAC prices for METFORMIN ER 500 MG OSMOTIC TB?
Since Dec 3, 2025, the NADAC for METFORMIN ER 500 MG OSMOTIC TB has ranged from a low of $0.1017 (Apr 22, 2026) to a high of $0.1644 (Sep 30, 2026), with a median of $0.1139 per EA.
Are there cheaper alternatives to METFORMIN ER 500 MG OSMOTIC TB?
Yes. 21 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN HCL 500 MG TABLET, is $0.0145 per EA — about 91% below METFORMIN ER 500 MG OSMOTIC TB.
Who manufactures METFORMIN ER 500 MG OSMOTIC TB?
METFORMIN ER 500 MG OSMOTIC TB (NDC 59651004260) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.