Product Information

LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB is a generic product labeled by Jubilant Cadista Pharmaceuticals Inc., priced at $0.0797 per EA under NDC 59746033730. Its NADAC has been published 614 times since Nov 28, 2013.

FDA first approved this application on Sep 18, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the losartan potassium and hydrochlorothiazide market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB

losartan potassium and hydrochlorothiazide
$0.0797per EA
High Outlier

Strength

12.5; 50 mg/1; mg/1

NDC

59746033730

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/20/2025

Approval Type

Generic (ANDA)

FDA Application

ANDA201845

FDA Approved

9/18/2012

TE Code

AB

On Market Since

10/30/2012

Pharmacological Classes

Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Blocker
Increased Diuresis
Thiazide Diuretic
Thiazides

Price Statistics

The NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has been published 614 times since Nov 28, 2013, and over the history we have for it it has declined 8.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0797 per EA
All-time high$0.1854 (Apr 15, 2020)
All-time low$0.0596 (Jan 23, 2019)
52-week high$0.0797
52-week low$0.0797
Median price$0.0876
Average price$0.1017
Largest weekly change+46.8% (Dec 18, 2019)
Weeks tracked614
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

0.0%

3Y

-22.2%

5Y

-47.6%

All

-8.1%

Last surveyed Aug 27, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 28% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB, manufactured by Jubilant Cadista Pharmaceuticals Inc., is $0.0797 per EA (NDC 59746033730), effective Aug 27, 2025.

How has the price of LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB changed over time?

Over the history we have for it, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has declined 8.1%. It has been tracked across 614 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

Since Nov 28, 2013, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has ranged from a low of $0.0596 (Jan 23, 2019) to a high of $0.1854 (Apr 15, 2020), with a median of $0.0876 per EA.

Are there cheaper alternatives to LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB, is $0.0573 per EA — about 28% below LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB.

Who manufactures LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB (NDC 59746033730) is labeled by Jubilant Cadista Pharmaceuticals Inc., and CMS classifies it as a generic product.