Product Information
LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB is a generic product labeled by Jubilant Cadista Pharmaceuticals Inc., priced at $0.0797 per EA under NDC 59746033730. Its NADAC has been published 614 times since Nov 28, 2013.
FDA first approved this application on Sep 18, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the losartan potassium and hydrochlorothiazide market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
12.5; 50 mg/1; mg/1
Manufacturer
Jubilant Cadista Pharmaceuticals Inc.NDC
59746033730
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/20/2025
Active Ingredients
HYDROCHLOROTHIAZIDE; LOSARTAN POTASSIUMApproval Type
Generic (ANDA)
FDA Application
ANDA201845FDA Approved
9/18/2012
TE Code
AB
On Market Since
10/30/2012
Pharmacological Classes
Price Statistics
The NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has been published 614 times since Nov 28, 2013, and over the history we have for it it has declined 8.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0797 per EA |
|---|---|
| All-time high | $0.1854 (Apr 15, 2020) |
| All-time low | $0.0596 (Jan 23, 2019) |
| Median price | $0.0876 |
| Average price | $0.1017 |
| Largest weekly change | +46.8% (Dec 18, 2019) |
| Weeks tracked | 614 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
-21.5%
5Y
-47.0%
All
-8.1%
Last surveyed Aug 27, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 30% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Jubilant Cadista Pharmaceuticals Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
losartan potassium and hydrochlorothiazide market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Angiotensin 2 Receptor Blocker class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB, manufactured by Jubilant Cadista Pharmaceuticals Inc., is $0.0797 per EA (NDC 59746033730), effective Aug 27, 2025.
How has the price of LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB changed over time?
Over the history we have for it, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has declined 8.1%. It has been tracked across 614 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?
Since Nov 28, 2013, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has ranged from a low of $0.0596 (Jan 23, 2019) to a high of $0.1854 (Apr 15, 2020), with a median of $0.0876 per EA.
Are there cheaper alternatives to LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB, is $0.0554 per EA — about 30% below LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB.
Who manufactures LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?
LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB (NDC 59746033730) is labeled by Jubilant Cadista Pharmaceuticals Inc., and CMS classifies it as a generic product.