Product Information

LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB is a generic product labeled by Jubilant Cadista Pharmaceuticals Inc., priced at $0.0754 per EA under NDC 59746033810. Its NADAC has been published 271 times since Jan 27, 2021.

FDA first approved this application on Sep 18, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the losartan potassium and hydrochlorothiazide market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB

losartan potassium and hydrochlorothiazide
$0.0754per EA
High Outlier

Strength

12.5; 100 mg/1; mg/1

NDC

59746033810

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

3/18/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA201845

FDA Approved

9/18/2012

TE Code

AB

On Market Since

10/30/2012

Pharmacological Classes

Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Blocker
Increased Diuresis
Thiazide Diuretic
Thiazides

Price Statistics

The NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB has been published 271 times since Jan 27, 2021, and over the history we have for it it has declined 57.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0754 per EA
All-time high$0.2088 (Apr 13, 2022)
All-time low$0.0746 (Nov 20, 2024)
52-week high$0.0973
52-week low$0.0754
Median price$0.1243
Average price$0.1294
Largest weekly change-24.9% (Nov 20, 2024)
Weeks tracked271
Tracking sinceJan 27, 2021

Price History

1W

N/A

1M

N/A

3M

N/A

6M

-3.0%

1Y

-22.6%

3Y

-40.1%

5Y

-52.8%

All

-57.3%

Last surveyed Apr 1, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB, manufactured by Jubilant Cadista Pharmaceuticals Inc., is $0.0754 per EA (NDC 59746033810), effective Apr 1, 2026.

How has the price of LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB changed over time?

Over the history we have for it, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB has declined 57.3%. It has been tracked across 271 weekly CMS publications since Jan 27, 2021.

What are the highest and lowest recorded NADAC prices for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?

Since Jan 27, 2021, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB has ranged from a low of $0.0746 (Nov 20, 2024) to a high of $0.2088 (Apr 13, 2022), with a median of $0.1243 per EA.

Are there cheaper alternatives to LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB, is $0.0750 per EA — about 1% below LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB.

Who manufactures LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB?

LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB (NDC 59746033810) is labeled by Jubilant Cadista Pharmaceuticals Inc., and CMS classifies it as a generic product.