Product Information

SIROLIMUS 0.5 MG TABLET is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.9386 per EA under NDC 59762100101. Its NADAC has been published 644 times since Apr 23, 2014.

FDA first approved this application on Aug 25, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

SIROLIMUS 0.5 MG TABLET

SIROLIMUS
$0.9386per EA

Strength

.5 mg/1

NDC

59762100101

Classification

Generic

Dosage Form

TABLET, SUGAR COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SIROLIMUS

Approval Type

Authorized Generic (NDA)

FDA Application

NDA021110

FDA Approved

8/25/2000

TE Code

AB

On Market Since

1/7/2014

Pharmacological Classes

Decreased Immunologic Activity
Kinase Inhibitor
Protein Kinase Inhibitors
mTOR Inhibitor Immunosuppressant
mTOR Inhibitors

Price Statistics

The NADAC for SIROLIMUS 0.5 MG TABLET has been published 644 times since Apr 23, 2014, and over the history we have for it it has declined 85.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.9386 per EA
All-time high$6.5979 (Feb 15, 2017)
All-time low$0.9386 (Aug 19, 2026)
52-week high$1.8082
52-week low$0.9386
Median price$5.2645
Average price$4.7115
Largest weekly change-50.5% (Sep 20, 2023)
Weeks tracked644
Tracking sinceApr 23, 2014

Price History

1W

-9.4%

1M

-9.4%

3M

-14.0%

6M

-42.1%

1Y

-48.1%

3Y

-59.8%

5Y

-80.3%

All

-85.0%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the SIROLIMUS market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of SIROLIMUS 0.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SIROLIMUS 0.5 MG TABLET, manufactured by Mylan Pharmaceuticals Inc., is $0.9386 per EA (NDC 59762100101), effective Aug 19, 2026.

How has the price of SIROLIMUS 0.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for SIROLIMUS 0.5 MG TABLET has declined 85.0%. It has been tracked across 644 weekly CMS publications since Apr 23, 2014.

What are the highest and lowest recorded NADAC prices for SIROLIMUS 0.5 MG TABLET?

Since Apr 23, 2014, the NADAC for SIROLIMUS 0.5 MG TABLET has ranged from a low of $0.9386 (Aug 19, 2026) to a high of $6.5979 (Feb 15, 2017), with a median of $5.2645 per EA.

Are there cheaper alternatives to SIROLIMUS 0.5 MG TABLET?

No other NADAC-published product currently shares the active ingredient and strength of SIROLIMUS 0.5 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures SIROLIMUS 0.5 MG TABLET?

SIROLIMUS 0.5 MG TABLET (NDC 59762100101) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.